DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf2 and chia.6

DIOPT Version :9

Sequence 1:	NP_477257.2	Gene:	Idgf2 / 34979	FlyBaseID:	FBgn0020415	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	NP_955897.2	Gene:	chia.6 / 322420	ZFINID:	ZDB-GENE-030131-1140	Length:	480	Species:	Danio rerio

Alignment Length:	452	Identity:	118/452 - (26%)
Similarity:	207/452 - (45%)	Gaps:	100/452 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 FTFVACLFAASTEAASNLVCYYDSSSYTREGLGKLLNPDLEIALQFCSHLVYGYAGLRGEN-LQA 70
            |:...|.|.    .||.||||:.:.|..|..:||.:..:::..|  |:||:|.::.:..|| |..
Zfish    10 FSLALCHFG----LASQLVCYFTNWSQYRPDVGKYMPSNVDPHL--CTHLIYAFSIINNENKLTT 68

  Fly    71 YSMNENLDIYKHQFSEVTSLKRKYPHLKVLLSVGGDHDIDPDHPNKYIDLLEGEKVRQIGFIRSA 135
            |..|:     :..:.....||:..|:||.||:|||.:    ....::..::...:.||. ||:|:
Zfish    69 YEWND-----ETLYQSFNGLKQSNPNLKTLLAVGGWN----FGTTQFSSMVSTPQNRQT-FIQSS 123

  Fly   136 YDLVKTYGFDGLDLAYQFP--KNKPRKVHGDLGLAWKSIKKLFTGDFIVDPHAALHKEQFTALVR 198
            ...::|:|||||||.:::|  :..|.:                            .|::||.|.:
Zfish   124 ITFLRTHGFDGLDLDWEYPGSRGSPPE----------------------------DKQRFTLLCK 160

  Fly   199 DVKDSLRADG-------FLLSLTVLP---NVNSTWYFDIPALNGLVDFVNLATFDF------LTP 247
            ::.::.:|:.       .:|:..|..   |:::.  ::|..:...:||:|:.|:||      :|
Zfish   161 ELVEAYQAESAATGRPRLMLTAAVAAGKGNIDAG--YEIAEIAKYLDFINIMTYDFHGSWESVT- 222

  Fly   248 ARNPEEADYSAPIYHPDGSKDRLAHLNADFQVEYWLSQGFPSNKINLGVATYGNAWKLTKDSGLE 312
                   .:::|:|...|......:.|.||.:.||..||.|..|:.:|.|.||..::|:......
Zfish   223 -------GHNSPLYRGSGDIGDKIYYNTDFAMTYWRDQGAPVEKLRMGFAAYGRTFRLSSAVSGV 280

  Fly   313 GVPVVPETSGPAPEGFQSQKPGLLSYAEICGKLSNPQNQFLKGNESPLRRVSDPTKRFGGIAYRP 377
            |.|    .||.|..|..:::.|..||.|||        .|||  ::.::::.|....:.
Zfish   281 GAP----ASGAASAGTYTREAGFWSYYEIC--------TFLK--QATVQQIVDQKVPYA------ 325

  Fly   378 VDGQITEG-IWVSYDDPDSASNKAAYARVKNLGGVALFDLSYDDFRGQ-CSGDKYPILRAIK 437
                 |:| .||.:|:.:|...|..|.:.|..||..::.|..|||.|| |...|||::..::
Zfish   326 -----TKGQEWVGFDNMESYKTKVDYLKEKGFGGAFVWALDLDDFSGQFCGQSKYPLIGQLR 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf2	NP_477257.2	GH18_IDGF	23..440	CDD:119352	113/436 (26%)
chia.6	NP_955897.2	Glyco_18	22..363	CDD:214753	104/415 (25%)
		GH18_chitolectin_chitotriosidase	23..385	CDD:119351	113/435 (26%)
		CBM_14	433..479	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592060
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.840