DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf2 and Idgf4

DIOPT Version :9

Sequence 1:	NP_477257.2	Gene:	Idgf2 / 34979	FlyBaseID:	FBgn0020415	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	NP_001285068.1	Gene:	Idgf4 / 31926	FlyBaseID:	FBgn0026415	Length:	442	Species:	Drosophila melanogaster

Alignment Length:	447	Identity:	248/447 - (55%)
Similarity:	317/447 - (70%)	Gaps:	12/447 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKAWIWFTFVACLFA---ASTEAASNLVCYYDSSSYTREGLGKLLNPDLEIALQFCSHLVYGYAG 62
            ||.:..|:.:....|   .|...:.:|:||||.:|:.||||.||:..|||.|||:|:||||||||
  Fly     1 MKLYALFSLLVGSLAIGQISAAGSHHLLCYYDGNSFVREGLSKLILTDLEPALQYCTHLVYGYAG 65

  Fly    63 LRGENLQAYSMNE--NLDIYKHQFSEVTSLKRKYPHLKVLLSVGGDHD-IDPDHPNKYIDLLEGE 124
            :...:.:..|.||  :||:....|.:||.||||||.||||||||||.| :||:: |||:.|||..
  Fly    66 INPSSNKLVSNNEKLDLDLGSSLFRQVTGLKRKYPALKVLLSVGGDKDTVDPEN-NKYLTLLESS 129

  Fly   125 KVRQIGFIRSAYDLVKTYGFDGLDLAYQFPKNKPRKVHGDLGLAWKSIKKLFTGDFIVDPHAALH 189
            ..| |.||.||:.||||||||||||.:|||||||:||||.:|..||..||:|:||.:||..|..|
  Fly   130 NAR-IPFINSAHSLVKTYGFDGLDLGWQFPKNKPKKVHGSIGKFWKGFKKIFSGDHVVDEKAEEH 193

  Fly   190 KEQFTALVRDVKDSLRADGFLLSLTVLPNVNSTWYFDIPALNGLVDFVNLATFDFLTPARNPEEA 254
            ||.||||||::|::.|.||::|.|:|||||||:.:||:||:...:|:|||.|:||.||.||.|.|
  Fly   194 KEAFTALVRELKNAFRPDGYILGLSVLPNVNSSLFFDVPAIINNLDYVNLHTYDFQTPERNNEVA 258

  Fly   255 DYSAPIYHPDGSKDRLAHLNADFQVEYWLSQGFPSNKINLGVATYGNAWKLTKDSGLEGVPVVPE 319
            |:.||||.   ..:|....|.::||:||.....|:.|||:|:||||.||||||||||.|:|.|.|
  Fly   259 DFPAPIYE---LNERNPEFNVNYQVKYWTGNRAPAAKINVGIATYGRAWKLTKDSGLTGLPPVAE 320

  Fly   320 TSGPAPEGFQSQKPGLLSYAEICGKLSNPQNQFLKGNESPLRRVSDPTKRFGGIAYRPVDGQITE 384
            ..|.||.|.|:|.|||||:.|:|.||.||.||.|||.:.|||:|.|||||||..|||..|.....
  Fly   321 ADGVAPAGTQTQIPGLLSWPEVCAKLPNPANQHLKGADGPLRKVGDPTKRFGSYAYRSADDSGEN 385

  Fly   385 GIWVSYDDPDSASNKAAYARVKNLGGVALFDLSYDDFRGQCSG-DKYPILRAIKYRL 440
            |:||.|:|||:|:.||.|.:.:.|||:|:.|||:|||||.|:| ||:||||.:|.:|
  Fly   386 GVWVGYEDPDTAAIKAEYVKREGLGGIAVVDLSFDDFRGGCTGHDKFPILRQVKSKL 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf2	NP_477257.2	GH18_IDGF	23..440	CDD:119352	242/420 (58%)
Idgf4	NP_001285068.1	GH18_IDGF	26..442	CDD:119352	242/420 (58%)
Idgf4	NP_001285068.1	Glyco_18	27..420	CDD:214753	228/397 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469720
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D227150at33208
OrthoFinder	1	1.000	-	-		FOG0008541
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850