DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf2 and RGD1309110

DIOPT Version :9

Sequence 1:	NP_477257.2	Gene:	Idgf2 / 34979	FlyBaseID:	FBgn0020415	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	XP_006233175.1	Gene:	RGD1309110 / 295352	RGDID:	1309110	Length:	440	Species:	Rattus norvegicus

Alignment Length:	452	Identity:	115/452 - (25%)
Similarity:	185/452 - (40%)	Gaps:	101/452 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LFAASTEAASNLVCYYDS-SSYTREGLGKLLNPDLEIALQFCSHLVYGYAGLRGENLQAYSMNEN 76
            |.....::|..|:||::: ..|..:..|..|: |::..|  |:||:|.:||: .||....:..::
  Rat    30 LLNVQLDSAYQLMCYFNNWPQYQPDVRGMKLD-DIDPCL--CTHLIYSFAGI-WENNNTMTKRKD 90

  Fly    77 LDIYKHQFSEVTSLKRKYPHLKVLLSVG------GDHDIDPDHPNKYIDLLEGEKVRQIGFIRSA 135
            ||.||    |...||::...||.|||:|      |          .:|.::...:.|.. ||.|.
  Rat    91 LDDYK----EFNDLKKRNNKLKTLLSIGCWNFEAG----------LFITMVSTPESRHT-FITSV 140

  Fly   136 YDLVKTYGFDGLDLAYQFPKNKPRKVHGDLGLAWKSIKKLFTGDFIVDPHAALHKEQFTALVRDV 200
            ...::.||||||:||:|:|        |..|...|. |.|||         .|.:|...|..::|
  Rat   141 RKFLRKYGFDGLNLAWQYP--------GCYGSPPKD-KHLFT---------ILTQEIRKAFEKEV 187

  Fly   201 KDSLRADGFLLSLTVLPNVNSTWYF--DIPALNGLVDFVNLATFDFLTPARNPEEADY---SAPI 260
            ..:.::.  |:....|..|.|...|  .:|.|:..:|::.:.|:|.     :.....|   ::|:
  Rat   188 SKNKKSR--LIITAALAGVISPIQFGYHVPQLSQSLDYIQVMTYDL-----HGSWDGYTGENSPL 245

  Fly   261 YHPDGSKDRLAHLNADFQVEYWLSQGFPSNKINLGVATYGNAWKLTKDSGLE-GVPVVPETSGPA 324
            |.........|..|..:.:..|.::|....|:.:|...||:.:.|:..:..| |   .|...|..
  Rat   246 YKSPAETGVKAFYNIKYTMHNWKNKGVSPEKLIVGFPAYGHTFILSDSTKTEIG---APSNRGGH 307

  Fly   325 PEGFQSQKPGLLSYAEICGKLSNPQNQF----------LKGNESPLRRVSDPTKRFGGIAYRPVD 379
            | |..::|.|..:|.|||..|.|...|.          ..|||
  Rat   308 P-GPYTKKTGFWAYYEICAFLKNGAIQVWNAAQQVPYAFHGNE---------------------- 349

  Fly   380 GQITEGIWVSYDDPDSASNKAAYARVKNLGGVALFDLSYDDFRGQ-CSGDKYPILRAIKYRL 440
                   ||.||:..|...||.:.:..|.||..::.:..||:.|. |....:|:...:|..|
  Rat   350 -------WVGYDNVKSFHIKAQWLKNNNFGGAMIWAIGMDDYTGSFCDQGPFPLTSTLKNAL 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf2	NP_477257.2	GH18_IDGF	23..440	CDD:119352	112/440 (25%)
RGD1309110	XP_006233175.1	GH18_chitolectin_chitotriosidase	41..404	CDD:119351	112/439 (26%)
RGD1309110	XP_006233175.1	Glyco_18	43..382	CDD:214753	105/415 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350369
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740