DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf2 and Chit1

DIOPT Version :9

Sequence 1:	NP_477257.2	Gene:	Idgf2 / 34979	FlyBaseID:	FBgn0020415	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	NP_001073157.1	Gene:	Chit1 / 289032	RGDID:	1305646	Length:	464	Species:	Rattus norvegicus

Alignment Length:	445	Identity:	129/445 - (28%)
Similarity:	215/445 - (48%)	Gaps:	85/445 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 VACLFAASTEAASNLVCYYDSSSYTREGLGKLLNPDLEIALQFCSHLVYGYAGLRGENLQAYSMN 74
            |..|......:|:.|.||:.:.:..|.|..:.|..|::..|  |:|::|.:|||....:.....|
  Rat    10 VTTLLMIQWGSAAKLFCYFTNWAQYRSGAARFLPRDVDPNL--CTHVIYAFAGLNNHQVSTVEPN 72

  Fly    75 ENLDIYKHQFSEVTSLKRKYPHLKVLLSVGGDHDIDPDHPNKYIDLLEGEKVRQIGFIRSAYDLV 139
            :.|     .:.|:.|||::.|.||.||:|||    ......|:.|::.....||. |:.||...:
  Rat    73 DEL-----FYQELNSLKKRNPKLKTLLAVGG----WSFGTQKFTDMVATASTRQT-FVNSALSFL 127

  Fly   140 KTYGFDGLDLAYQFPKNKPRKVHGDLGLAWKSIKKLFTGDFIVDPHAALHKEQFTALVRDV---- 200
            :|:|||||||.:::|        |..|                  ..|:.||:||||::|:
  Rat   128 RTHGFDGLDLDWEYP--------GSRG------------------SPAVDKERFTALIQDLAKAF 166

  Fly   201 KDSLRADG--FLLSLTVLP----NVNSTWYFDIPALNGLVDFVNLATFDFLTPARNPEEADYSAP 259
            ::..||.|  .||....:|    :|::.  :::..:...:||:||..:||  .:...:...:::|
  Rat   167 QEEARASGKSRLLLTAAVPTGRGHVDAG--YEVDKIVQSLDFINLMAYDF--HSSWDKTTGHNSP 227

  Fly   260 IYHPDGSKDRLAHLNADFQVEYWLSQGFPSNKINLGVATYGNAWKL--TKDSGLEGVPVVPETSG 322
            :|...|...:.|..|.|..|..||.:|.|::|:.||:..||.::.|  :.|||: |.|    .:|
  Rat   228 LYKRQGETGKDAEKNVDAAVTLWLQKGTPASKLMLGMPAYGRSFTLASSSDSGV-GAP----ATG 287

  Fly   323 PAPEGFQSQKPGLLSYAEICGKLSNPQNQFLKGNESPLRRVSDPTKRFGGIAYRPVDGQITEG-I 386
            |...|..:::.|:|.|.|:|.         .||.:    |:.|..     :.|      :::| .
  Rat   288 PGAPGPYTKEKGILVYFEVCS---------WKGKQ----RIEDQK-----VPY------VSQGNQ 328

  Fly   387 WVSYDDPDSASNKAAYARVKNLGGVALFDLSYDDFRGQ-CSGDKYPILRAIKYRL 440
            ||.:||.:|...||||.:.|.|||..::.|..|||:|. |:..:||::|.:...|
  Rat   329 WVGFDDRESFRAKAAYVKQKGLGGAMVWILDGDDFKGSFCNEGQYPLIRTLHQEL 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf2	NP_477257.2	GH18_IDGF	23..440	CDD:119352	125/430 (29%)
Chit1	NP_001073157.1	GH18_chitolectin_chitotriosidase	24..383	CDD:119351	125/429 (29%)
Chit1	NP_001073157.1	ChtBD2	416..463	CDD:214696
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350393
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11177
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.940