DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf2 and Cht12

DIOPT Version :9

Sequence 1:	NP_477257.2	Gene:	Idgf2 / 34979	FlyBaseID:	FBgn0020415	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	NP_726022.1	Gene:	Cht12 / 246535	FlyBaseID:	FBgn0050293	Length:	470	Species:	Drosophila melanogaster

Alignment Length:	427	Identity:	96/427 - (22%)
Similarity:	175/427 - (40%)	Gaps:	92/427 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 NLVCYYDSSSYTREGLGKLLNPDLEIALQFCSHLVYGYA-GLRGENLQAYSMNENLDIYKHQFSE 86
            |:.|.||..||..:|..:.....|:..|  |:|||.|.. |:.|::.:....::.|.:.|.:.|.
  Fly    24 NVFCQYDLGSYYYKGRSQFFEWHLDSRL--CTHLVLGSGIGVDGDSGELRITDKILLLEKDKLSS 86

  Fly    87 VTSLKRKYPHL-KVLLSVGG-DHDIDPDHPNKYIDLLEGEKVRQIGFIRSAYDLVKTYGFDGLDL 149
            |.::  |:..: ||:.::|| :.|     .:.:..::...|.|. .|..|..:.:..:||||:.:
  Fly    87 VKTM--KWDSIKKVMFTIGGWEED-----SSSFSRMVASPKKRD-NFYSSMLEFMFRWGFDGVQI 143

  Fly   150 AYQFPKNKPRKVHGDLGLAWKSIKKLFTGDFIVDPHAALHKEQFTALVRDVKDSLRADGFLLSLT 214
            .:::|.                         ::..|.. .::.|..|:.::....|.:..:|.:.
  Fly   144 DWRYPT-------------------------LLGGHPD-DRQNFVILLEELGLIFRKNQLILMVA 182

  Fly   215 VLPNVNSTWY--FDIPALNGLVDFVNLATFDFLTPARNPEEAD-------YSAPIYHPDGS-KDR 269
            ||...::...  ::||.:....||::|...|         |.|       |:||:...:|| .|.
  Fly   183 VLGRRDNRILESYNIPEIVNHSDFIHLMMHD---------EQDPYHLRLAYNAPLVGYEGSVTDS 238

  Fly   270 LAHLNADFQVEYWLSQGFPSNKINLGVATYGNAWKLTKDSGLEGVPVVPETSGPAPEGFQSQKPG 334
            :.|         |...|....|:.||:..:..::.:.::....|    ....||..:..||.:||
  Fly   239 IMH---------WKRNGGAPEKLILGIPLFVRSFTMDRNQSTVG----SACKGPGRQTKQSHRPG 290

  Fly   335 LLSYAEICGKLSNPQNQFLKGNESPLRRVSDPTKRFGGIAYRPVDGQITEGIWVSYDDPDSASNK 399
            .::|.|.|.:.|.....|.:..:.|.....|.                    ||||::|.|...|
  Fly   291 FMTYNEWCVQQSKWSRMFDQLAKVPYATRGDQ--------------------WVSYENPRSIWAK 335

  Fly   400 AAYARVKNLGGVALFDLSYDDFRGQCSGDKYPILRAI 436
            ....:...|||...:.:..|||||:| |:::.:||.|
  Fly   336 MHLLQEHKLGGAMAWTIDVDDFRGRC-GEQHGLLRVI 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf2	NP_477257.2	GH18_IDGF	23..440	CDD:119352	96/427 (22%)
Cht12	NP_726022.1	GH18_chitinase-like	25..375	CDD:299167	95/426 (22%)
		Glyco_hydro_18	47..355	CDD:279094	79/385 (21%)
		ChtBD2	394..438	CDD:214696
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463818
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840