DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf2 and lmd-5

DIOPT Version :9

Sequence 1:	NP_477257.2	Gene:	Idgf2 / 34979	FlyBaseID:	FBgn0020415	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	NP_001309512.1	Gene:	lmd-5 / 187942	WormBaseID:	WBGene00020141	Length:	1518	Species:	Caenorhabditis elegans

Alignment Length:	479	Identity:	90/479 - (18%)
Similarity:	175/479 - (36%)	Gaps:	166/479 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 AASTEAAS---NLVCYY---DSSSYTREGLGKLLNPDLEIALQFCSHLVYGYAGLRGENLQAYSM 73
            ::|..|||   .:|.||   .....|...|.||            :|:::.:..:..:.
Worm   980 SSSVPAASCGKRIVGYYTGWGEREITENQLKKL------------THVIFAFVAMYADG------ 1026

  Fly    74 NENLDIYKHQFSEVTS----------LKRKYPHLK-----------VLLSVGG-DHDIDPDHPNK 116
                   ..:|..|::          .:|::..:|           ||.:||| |:       ::
Worm  1027 -------SVKFGPVSADDPGPQAGKKAERRFVDMKKKARAVNSGVRVLFAVGGWDN-------SQ 1077

  Fly   117 YIDLLEGEKVRQIGFIRSAYDLVKTYGFDGLDLAYQFPKNKPRKVHGDLGLAWKSIKKLFTGDFI 181
            |...:..:..::..|:.|....::.:..||:||.:::|:.|                   .||
Worm  1078 YFSSVAADSGKRRNFVDSVASFIEHHKIDGVDLDWEYPEMK-------------------GGD-- 1121

  Fly   182 VDPHAALHKEQFTALVRDVKDSL--------RADGFLLSLTVLPNVNSTWY----FDIPALNGLV 234
                    |:....|:|::::..        |.|.:|::|.   :....|.    :|:..:....
Worm  1122 --------KQNHVTLIRELRERFNGMASRNNRKDPYLITLA---SAAGEWNLREGYDLKGILNYA 1175

  Fly   235 DFVNLATFDFL------------TPARNPEEADYSAPIYHPDGS-KDRLAHLNADFQVEYWLSQG 286
            ||:|:.|:|:.            ||          ||:|.  || |.....|||||.::::....
Worm  1176 DFINVMTYDYYGAWESKWGAYTGTP----------APLYF--GSLKGFSGKLNADFSMKFYACNT 1228

  Fly   287 FPSNKINLGVATYGNAWKLTKDSGLEGVPV---VPETSGPAPEGFQSQKPGLLSYAEICGKLSNP 348
            ...:::.:||..||..||    :.||.:..   :..|:.|....::.   |.:.:..:      .
Worm  1229 KKPSQLTMGVPFYGRYWK----NVLEPIDASDNMWRTAAPQNGKYEG---GYVGWRNL------E 1280

  Fly   349 QNQFLKGNESPLRRVSDPTKRFGGIAYRPVDGQITEGIWVSYDDPDSASNKAAYARVKNLGGVAL 413
            :..:.||:.:..::...|.....|..           :::.:::..|...|..||..:||||:.:
Worm  1281 KEGWNKGSATWHKKTKTPYIMNNGAR-----------MFLGFENERSLKEKMDYATNRNLGGLMI 1334

  Fly   414 FDLSYDD----------FRGQCSG 427
            :.|..||          ..|.|||
Worm  1335 WALDLDDDADTLLNLVSSAGLCSG 1358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf2	NP_477257.2	GH18_IDGF	23..440	CDD:119352	86/468 (18%)
lmd-5	NP_001309512.1	LysM	22..65	CDD:197609
		LysM	77..120	CDD:197609
		LysM	151..194	CDD:197609
		LysM	220..260	CDD:197609
		LysM	275..312	CDD:197609
		LysM	386..429	CDD:197609
		Self-incomp_S1	851..944	CDD:283566
		Glyco_18	991..1336	CDD:214753	79/444 (18%)
		GH18_chitinase-like	992..1336	CDD:299167	79/443 (18%)
		ChtBD1_GH18_2	1388..1435	CDD:211315
		ChtBD1_GH18_2	1462..1513	CDD:211315
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164433
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.700