DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf2 and chil-8

DIOPT Version :9

Sequence 1:	NP_477257.2	Gene:	Idgf2 / 34979	FlyBaseID:	FBgn0020415	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	NP_001379090.1	Gene:	chil-8 / 174541	WormBaseID:	WBGene00007473	Length:	399	Species:	Caenorhabditis elegans

Alignment Length:	448	Identity:	96/448 - (21%)
Similarity:	185/448 - (41%)	Gaps:	134/448 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LFAASTEAASNLVCY-YDSSS--------YTREGLGKLLNPD-LEIA---LQFCSHLVYGYAGLR 64
            :|...:...|:|.|| ||.|:        :.:..:|.:.:.: .||.   |:..:|:::.:..:.
Worm    17 VFGIVSFLVSSLFCYFYDFSNSVQSPSVLHRKRIIGYVSSDEGSEITIKQLEKLTHVIFAFILVH 81

  Fly    65 GENLQAYSMNENLDIYKHQFSEVTSLKRKYPH----LKVLLSVGGDHDIDPDHPNKYIDLLEGEK 125
            .:....:....     |..|.:   :|||...    |||::|:|| ::..|    .:.|:|..:|
Worm    82 KDGTIKFKYGT-----KDGFFD---MKRKSMELNRGLKVMVSIGG-YESSP----LFSDVLVKKK 133

  Fly   126 VRQIGFIRSAYDLVKTYGFDGLDLAYQFPKNKPRKVHGDLGLAWKSIKKLFTGDFIVDPHAALHK 190
            .:.|..|..   |||.:..||:|:.:.:|.                         |.|      :
Worm   134 KKLIASIAL---LVKKFDLDGVDIFWNWPS-------------------------ITD------Q 164

  Fly   191 EQFTALVRDVKDSL--------RADGFLLSLTVLPNVNSTWYFDIP----ALNGLVDFVNLATFD 243
            ..:...:|:::..|        |::.:::|: :.|:.:|  :.:.|    .:...|||:|:.||:
Worm   165 SNYLIFIRELRKKLTNLKDENGRSNEYVISV-IAPSSSS--HSEYPYKWTEILENVDFINVITFE 226

  Fly   244 FLTPAR--NPEEADYSAPIYHPDGSKDRLAHLNADFQVEYWLSQGFPSNKINLGVATYGNAWKLT 306
            :...|.  .|.     :|:|  .||..     |.|..::|.:.:....||:|:.|:..|..|..|
Worm   227 YFYEANKIGPH-----SPLY--GGSFG-----NVDDTLKYLICRTRTPNKLNMVVSFNGIYWGNT 279

  Fly   307 ----KDSGLEGVPVVPETSGPAPEGFQSQKPGLLSYAEICGKLSN--PQNQFLKGNE---SPLRR 362
                .|.|:    .:|:.|...|..:     |...:|    ::|:  .||.| :.||   :|...
Worm   280 TLPFDDKGV----WIPDDSAQGPYSY-----GWKQFA----RMSHGFDQNDF-EWNEETRTPYIW 330

  Fly   363 VSDPTKRFGGIAYRPVDGQITEGIWVSYDDPDSASNKAAYARVKNLGGVALFDLSYDD 420
            .:| |::|                 :::::..|.:.|..||...|:||||::.:..||
Worm   331 KAD-TQQF-----------------LTFENEKSLTEKMNYAVAHNIGGVAMYTIDDDD 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf2	NP_477257.2	GH18_IDGF	23..440	CDD:119352	94/438 (21%)
chil-8	NP_001379090.1	Glyco_18	49..369	CDD:214753	86/413 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164430
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.700