Protein Alignment Idgf2 and Chi3l1

DIOPT Version :10

• Sequence 1: NP_477257.2
• Gene: Idgf2 / 34979
• FlyBaseID: FBgn0020415
• Length: 440
• Species: Drosophila melanogaster
• Sequence 2: NP_031721.2
• Gene: Chi3l1 / 12654
• MGIID: 1340899
• Length: 389
• Species: Mus musculus
• Alignment Length: 437
• Identity: 125/437 - (28%)
• Similarity: 205/437 - (46%)
• Gaps: 74/437 - (16%)

  Fly     8 TFVACLFAASTEAASNLVCYYDSSSYTREGLGKLLNPDLEIALQ--FCSHLVYGYAGLRGEN-LQ 69
            |..|.|....:.:|..||||:.|.|..|||:|..| ||   |:|  .|:|::|.:|.:..:| |.
Mouse    16 TGFAVLMLLQSCSAYKLVCYFTSWSQYREGVGSFL-PD---AIQPFLCTHIIYSFANISSDNMLS 76

  Fly    70 AYSMNENLDIYKHQFSEVTSLKRKYPHLKVLLSVGGDHDIDPDHPNKYIDLLEGEKVRQIGFIRS 134
            .:..|:     :..:.::..||.:..:||.||||||     .....|....:.....|:..|:||
Mouse    77 TWEWND-----ESNYDKLNKLKTRNTNLKTLLSVGG-----WKFGEKRFSEIASNTERRTAFVRS 131

  Fly   135 AYDLVKTYGFDGLDLAYQFPKNKPRKVHGDLGLAWKSIKKLFTGDFIVDPHAALHKEQFTALVRD 199
            ....:::|||||||||:.:|:.:.::....|      ||:|              ..:||..|:.
Mouse   132 VAPFLRSYGFDGLDLAWLYPRLRDKQYFSTL------IKEL--------------NAEFTKEVQP 176

  Fly   200 VKDSLRADGFLLSLTVLPNVNSTWYFDIPALNGLVDFVNLATFDFLTPARNPEEADYSAPIYHPD 264
            .::.|.....|.:..|..:..    :||..:...:||:||.|:||....|  :...:.:|::  .
Mouse   177 GREKLLLSAALSAGKVAIDTG----YDIAQIAQHLDFINLMTYDFHGVWR--QITGHHSPLF--Q 233

  Fly   265 GSKDRL--AHLNADFQVEYWLSQGFPSNKINLGVATYGNAWKLTKDSGLEGVPVVPETSGPAPEG 327
            |.||..  .:.|.::.|:|.:..|..::|:.:|:.|:|.::.|.......|.|:    ||....|
Mouse   234 GQKDTRFDRYSNVNYAVQYMIRLGAQASKLLMGIPTFGKSFTLASSENQLGAPI----SGEGLPG 294

  Fly   328 FQSQKPGLLSYAEICGKLSNPQNQFLKGNESPLRRVSDPTKRFGGIAYRPVDGQITEG-IWVSYD 391
            ..:::.|.|:|.|||        .||||.|  :.|:|:....|.           |:| .||.|:
Mouse   295 RFTKEAGTLAYYEIC--------DFLKGAE--VHRLSNEKVPFA-----------TKGNQWVGYE 338

  Fly   392 DPDSASNKAAYARVKNLGGVALFDLSYDDFRGQCSGDK-YPILRAIK 437
            |.:|..||..:.:.|.|.|..::.|..|||:|.|...: :|:..|||
Mouse   339 DKESVKNKVGFLKEKKLAGAMVWALDLDDFQGTCQPKEFFPLTNAIK 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Idgf2	NP_477257.2	GH18_IDGF	23..440	CDD:119352	121/422 (29%)
Chi3l1	NP_031721.2	GH18_chitolectin_chitotriosidase	32..388	CDD:119351	121/421 (29%)
		Important for AKT1 activation and IL8 production	333..347		6/13 (46%)