back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Idgf2 and Chia

DIOPT Version :9

Sequence 1:	NP_477257.2	Gene:	Idgf2 / 34979	FlyBaseID:	FBgn0020415	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	NP_997469.1	Gene:	Chia / 113901	RGDID:	1303058	Length:	473	Species:	Rattus norvegicus

Alignment Length:	465	Identity:	121/465 - (26%)
Similarity:	200/465 - (43%)	Gaps:	103/465 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKAWIWFTFVACLFAASTEAASNLVCYYDSSSYTREGLGKLLNPDLEIALQFCSHLVYGYAGLRG 65
            |...|..|.:..|......:|.|||||:.:.:..|.|||.....|:...|  |:||:|.:||::.
  Rat     1 MAKLILVTGLVLLLNVQLGSAYNLVCYFTNWAQYRPGLGSFKPDDINPCL--CTHLIYAFAGMQN 63

  Fly    66 ENLQAYSMNENLDIYKHQFSEVTSLKRKYPHLKVLLSVGG-DHDIDPDHPNKYIDLLEGEKVRQI 129
            ..:.....|: :.:|| .|::   ||.:...||.||::|| :....|     :..::...:.||.
  Rat    64 NQITTIEWND-VTLYK-AFND---LKNRNSKLKTLLAIGGWNFGTAP-----FTTMVSTSQNRQT 118

  Fly   130 GFIRSAYDLVKTYGFDGLDLAYQFPKNKPRKVHGDLGLAWKSIKKLFTGDFIVDPHAALHKEQFT 194
             ||.|....::.||||||||.:::|.::                    |....|.|.      ||
  Rat   119 -FITSVIKFLRQYGFDGLDLDWEYPGSR--------------------GSPPQDKHL------FT 156

  Fly   195 ALVRDVKDSLRADG-------FLLSLTVLPNV-NSTWYFDIPALNGLVDFVNLATFDFLTPARNP 251
            .||::::::...:.       .:::..|...: |....::||.|:..:||:::.|:|.     :.
  Rat   157 VLVKELREAFEQEAIESNRPRLMVTAAVAAGISNIQAGYEIPELSQYLDFIHVMTYDL-----HG 216

  Fly   252 EEADY---SAPIYHPDGSKDRLAHLNADFQVEYWLSQGFPSNKINLGVATYGNAWKLT--KDSGL 311
            ....|   ::|:|.........|:||.|:.:.||...|.|:.|:.:|...||:.:.|:  .|:|:
  Rat   217 SWDGYTGENSPLYKLPTETGSNAYLNVDYVMNYWKDNGAPAEKLIVGFPEYGHTYILSNPSDTGI 281

  Fly   312 EGVPVVPETSGPAPEGFQSQKPGLLSYAEICGKLSNPQNQ----------FLKGNESPLRRVSDP 366
             |.|    |||..|.|..:::.|..:|.|||..|.|...|          ..||||
  Rat   282 -GAP----TSGNGPAGPYTRQAGFWAYYEICTFLRNGATQDWDAPQEVPYAYKGNE--------- 332

  Fly   367 TKRFGGIAYRPVDGQITEGIWVSYDDPDSASNKAAYARVKNLGGVALFDLSYDDFRGQ-CSGDKY 430
                                ||.||:..|.|.||.:.:..|.||..::.:..|||.|. |...|:
  Rat   333 --------------------WVGYDNIKSFSVKAQWLKQNNFGGAMIWAIDLDDFTGSFCDQGKF 377

  Fly   431 PILRAIKYRL 440
            |:...:...|
  Rat   378 PLTSTLNKAL 387

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.