DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf1 and chia.1

DIOPT Version :9

Sequence 1:	NP_477258.1	Gene:	Idgf1 / 34978	FlyBaseID:	FBgn0020416	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_998215.1	Gene:	chia.1 / 406323	ZFINID:	ZDB-GENE-040426-1994	Length:	455	Species:	Danio rerio

Alignment Length:	452	Identity:	110/452 - (24%)
Similarity:	190/452 - (42%)	Gaps:	95/452 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LGLLSVTSLTHAASNLICYYDSNSYLRQGLAKMHTNELDLALQFCTHLVYGYAGLK-SGTLELFS 72
            ||:|....:. :::.|:||..:.|..|.|..|.....:|..|  |||:||..|.:. ...:....
Zfish    10 LGILLSLQIV-SSTKLVCYMTNWSQYRPGNGKFLPENIDPFL--CTHVVYALATISYDNQITTIE 71

  Fly    73 LNVDLDMFYYKDITALRQKFPQLKILLSVGGDRDVDEAHPNKYVELLEA--NRTAQQNFIDSSMI 135
            .| |:|:  ||.:..|::..|.||..|||||  .|:...|  |:.::..  ||.|   ||.::::
Zfish    72 WN-DVDL--YKSMNELKKVNPALKTQLSVGG--LVNGVSP--YINMVATPENRKA---FIRNALL 126

  Fly   136 LLKRNGFDGLDLAFQLPRNKPRKVHGSLGSYWKSFKKLFTGDFVVDPQAEEHKSQFTDLVGNIKN 200
            .|:.:.|||:|:.:|.|        |..||               .||   .|.:.|..:..:::
Zfish   127 FLRLHEFDGMDIDWQYP--------GHNGS---------------PPQ---DKQRLTTFIKEMRD 165

  Fly   201 AF-------RSANLMLSL------TVLPNVNSTWYFDVPKLHPQFDYINLAAFDF---LTPLRNP 249
            |.       :...|:||:      |.:.|.     ::..::....|::.:.::|:   ..|:
Zfish   166 AIEQEAIDTKKTPLLLSIKVSAIKTTIENA-----YEAKEVASLVDFVTIMSYDYHGHWDPI--- 222

  Fly   250 EEADFTAPIFFQD-EQNRLPHLNVEFQINYWLQNHCPGQKLNLGIASYGRAWKLSKGSGLSGAPI 313
              ....:|:|... :...:.|.|:...:.:||.:..|..:|.||:.:|||.:.||......|||
Zfish   223 --TGHNSPLFRSSFDTGSIVHHNINSSLEFWLGSGAPADRLLLGLPTYGRTFMLSTSQTGLGAP- 284

  Fly   314 VHETCGVAPGGIQIQSAEGLLSWPEICSKLSQNASAQYRGELAPLRKVTDLTQKYGNYALRPADD 378
               ..|.|..|...:.| |..|:.|||...|.........::.|             ||::..
Zfish   285 ---ANGPADAGPYTREA-GFWSYYEICPMESSVPIHWIDEQMVP-------------YAVQGR-- 330

  Fly   379 NGDFGVWLSFDDPDFAGIKAVYAKGKGLGGIALFDLSYDDFRG-LCTGQKYPILRSIKYFMG 439
                 .|:.||:.:....|..:.....|||.:::.|.:|||.| .|....||::..::..:|
Zfish   331 -----AWVGFDNQESITAKVQWLNSLKLGGASVWTLDFDDFAGRFCYNGAYPLVNHLRNSLG 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf1	NP_477258.1	GH18_IDGF	23..438	CDD:119352	106/435 (24%)
Idgf1	NP_477258.1	Glyco_18	24..417	CDD:214753	99/412 (24%)
chia.1	NP_998215.1	Glyco_18	23..364	CDD:214753	99/413 (24%)
		GH18_chitolectin_chitotriosidase	24..386	CDD:119351	106/434 (24%)
		ChtBD2	407..455	CDD:214696
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592095
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.940