DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf1 and Idgf5

DIOPT Version :9

Sequence 1:	NP_477258.1	Gene:	Idgf1 / 34978	FlyBaseID:	FBgn0020416	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_611321.3	Gene:	Idgf5 / 37104	FlyBaseID:	FBgn0064237	Length:	444	Species:	Drosophila melanogaster

Alignment Length:	441	Identity:	189/441 - (42%)
Similarity:	281/441 - (63%)	Gaps:	21/441 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LGLLSVTSL-----THA-ASNLICYYDSNSYLRQGLAKMHTNELDLALQFCTHLVYGYAGLKSGT 67
            ||||..:.|     |:| ...|:|:||:.|::|:|.|:|...||:.|||||..|||||||:.:.|
  Fly    10 LGLLLCSFLAFFQSTYAEVGKLVCFYDAQSFVREGPAQMSLAELEPALQFCNFLVYGYAGIDAVT 74

  Fly    68 LELFSLNVDL--DMFYYKDITALRQKFPQLKILLSVGGDRDVDE---AHPNKYVELLEANRTAQQ 127
            .::.||:..|  |..:|:.|||||:|:|.::.||||||||||:.   |..:||:.|||.:. .::
  Fly    75 YKIKSLDPSLTNDRQHYRHITALRKKYPHVRFLLSVGGDRDVNSEGVADSDKYLRLLEQSE-HRK 138

  Fly   128 NFIDSSMILLKRNGFDGLDLAFQLPRNKPRKVHGSLGSYWKSFKKLFTGDFVVDPQAEEHKSQFT 192
            :|..|.:..|..|||||:|||:|.|:|:|:...|.....|.|.:..|:.. .||.::|||:.||.
  Fly   139 SFQASVLAELNNNGFDGIDLAWQFPKNRPKLQQGVFKRVWGSLRGWFSSS-SVDEKSEEHREQFA 202

  Fly   193 DLVGNIKNAFRSANLMLSLTVLPNVNSTWYFDVPKLHPQFDYINLAAFDFLTPLRNPEEADFTAP 257
            .|:..:::..|....:|::::||:|::..:.||||:....|::||..:||.||.|:|:.||...|
  Fly   203 TLLEELQSDLRRGGQLLTVSMLPHVSAELFIDVPKVLSNVDFVNLGTYDFQTPERDPKVADLPTP 267

  Fly   258 IFFQDEQNRLPHLNVEFQINYWLQ--NHCPGQKLNLGIASYGRAWKLSKGSGLSGAPIVHETCGV 320
            ::..  .:|.|..||::|:.||:.  :.....||::|:.||||||.:::.||::|.|.:....|.
  Fly   268 LYAM--YDRDPSHNVQYQVQYWMNQTSEISVHKLHVGVTSYGRAWNMTRNSGITGYPPIPAANGA 330

  Fly   321 APGGIQIQSAEGLLSWPEICSKLSQNASAQYRGELAPLRKVTDLTQKYGNYALRPADDNGDFGVW 385
            ||.|.|..: .|||||||||..|.|....:   |:..||||.|.|:::|.||.|.|||.|:.|:|
  Fly   331 APPGRQTVT-PGLLSWPEICDLLQQQPQDR---EVPHLRKVGDPTKRFGIYAYRAADDQGENGLW 391

  Fly   386 LSFDDPDFAGIKAVYAKGKGLGGIALFDLSYDDFRGLCTGQKYPILRSIKY 436
            :.::||..|.|||.:...:||||:|..|||.|||||.|.|:|:|||||||:
  Fly   392 VGYEDPLTAAIKAGFVHAQGLGGVAFHDLSMDDFRGQCAGEKFPILRSIKF 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf1	NP_477258.1	GH18_IDGF	23..438	CDD:119352	182/421 (43%)
Idgf1	NP_477258.1	Glyco_18	24..417	CDD:214753	167/399 (42%)
Idgf5	NP_611321.3	GH18_IDGF	30..444	CDD:119352	182/421 (43%)
Idgf5	NP_611321.3	Glyco_18	30..423	CDD:214753	167/400 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469728
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D227150at33208
OrthoFinder	1	1.000	-	-		FOG0008541
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850