DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf1 and Chit1

DIOPT Version :9

Sequence 1:	NP_477258.1	Gene:	Idgf1 / 34978	FlyBaseID:	FBgn0020416	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_001073157.1	Gene:	Chit1 / 289032	RGDID:	1305646	Length:	464	Species:	Rattus norvegicus

Alignment Length:	448	Identity:	131/448 - (29%)
Similarity:	219/448 - (48%)	Gaps:	95/448 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LGLLSVTSLT----HAASNLICYYDSNSYLRQGLAKMHTNELDLALQFCTHLVYGYAGLKSGTLE 69
            |.|..||:|.    .:|:.|.||:.:.:..|.|.|:....::|..|  |||::|.:|||.:..:.
  Rat     5 LALAGVTTLLMIQWGSAAKLFCYFTNWAQYRSGAARFLPRDVDPNL--CTHVIYAFAGLNNHQVS 67

  Fly    70 LFSLNVDLDMFYYKDITALRQKFPQLKILLSVGGDRDVDEAHPNKYVELLEANRTAQQNFIDSSM 134
            ....|   |..:|:::.:|:::.|:||.||:|||    ......|:.::: |..:.:|.|::|::
  Rat    68 TVEPN---DELFYQELNSLKKRNPKLKTLLAVGG----WSFGTQKFTDMV-ATASTRQTFVNSAL 124

  Fly   135 ILLKRNGFDGLDLAFQLPRNKPRKVHGSLGSYWKSFKKLFTGDFVVDPQAEEHKSQFTDLVGNIK 199
            ..|:.:|||||||.::.|        ||.||                |..:  |.:||.|:.::.
  Rat   125 SFLRTHGFDGLDLDWEYP--------GSRGS----------------PAVD--KERFTALIQDLA 163

  Fly   200 NAFR-------SANLMLSLTVLP----NVNSTWYFDVPKLHPQFDYINLAAFDFLTPLRNPEEAD 253
            .||:       .:.|:|:..| |    :|::.  ::|.|:....|:|||.|:||.:..  .:...
  Rat   164 KAFQEEARASGKSRLLLTAAV-PTGRGHVDAG--YEVDKIVQSLDFINLMAYDFHSSW--DKTTG 223

  Fly   254 FTAPIF-FQDEQNRLPHLNVEFQINYWLQNHCPGQKLNLGIASYGRAWKL--SKGSGLSGAPIVH 315
            ..:|:: .|.|..:....||:..:..|||...|..||.||:.:|||::.|  |..||: |||
  Rat   224 HNSPLYKRQGETGKDAEKNVDAAVTLWLQKGTPASKLMLGMPAYGRSFTLASSSDSGV-GAP--- 284

  Fly   316 ETCGVAPGGIQIQSAEGLLSWPEICSKLSQNASAQYRGELAPLRKVTDLTQKY---GNYALRPAD 377
            .|...|||  .....:|:|.:.|:||         ::|:    :::.|....|   ||.
  Rat   285 ATGPGAPG--PYTKEKGILVYFEVCS---------WKGK----QRIEDQKVPYVSQGNQ------ 328

  Fly   378 DNGDFGVWLSFDDPDFAGIKAVYAKGKGLGGIALFDLSYDDFRG-LCTGQKYPILRSI 434
                   |:.|||.:....||.|.|.|||||..::.|..|||:| .|...:||::|::
  Rat   329 -------WVGFDDRESFRAKAAYVKQKGLGGAMVWILDGDDFKGSFCNEGQYPLIRTL 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf1	NP_477258.1	GH18_IDGF	23..438	CDD:119352	125/430 (29%)
Idgf1	NP_477258.1	Glyco_18	24..417	CDD:214753	117/409 (29%)
Chit1	NP_001073157.1	GH18_chitolectin_chitotriosidase	24..383	CDD:119351	125/429 (29%)
Chit1	NP_001073157.1	ChtBD2	416..463	CDD:214696
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350394
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11177
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.940