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Protein Alignment Idgf1 and CHIA

DIOPT Version :9

Sequence 1:	NP_477258.1	Gene:	Idgf1 / 34978	FlyBaseID:	FBgn0020416	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_970615.2	Gene:	CHIA / 27159	HGNCID:	17432	Length:	476	Species:	Homo sapiens

Alignment Length:	454	Identity:	128/454 - (28%)
Similarity:	208/454 - (45%)	Gaps:	86/454 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 QLFYILGLLSVTSL-THAASNLICYYDSNSYLRQGLAKMHTNELDLALQFCTHLVYGYAGLKSGT 67
            :|..:.||:.:.:| ..:|..|.||:.:.:..|.||.:...:.:|..|  ||||:|.:||.::..
Human     3 KLILLTGLVLILNLQLGSAYQLTCYFTNWAQYRPGLGRFMPDNIDPCL--CTHLIYAFAGRQNNE 65

  Fly    68 LELFSLNVDLDMFYYKDITALRQKFPQLKILLSVGGDRDVDEAHPNKYVELLEANRTAQQNFIDS 132
            :.....|   |:..|:....|:.|..|||.||::|| .:...|.....|...| ||   |.||.|
Human    66 ITTIEWN---DVTLYQAFNGLKNKNSQLKTLLAIGG-WNFGTAPFTAMVSTPE-NR---QTFITS 122

  Fly   133 SMILLKRNGFDGLDLAFQLPRNKPRKVHGSLGSYWKSFKKLFTGDFVVDPQAEEHKSQFTDLVGN 197
            .:..|::..|||||..::.|        ||.||                |..::|  .||.||..
Human   123 VIKFLRQYEFDGLDFDWEYP--------GSRGS----------------PPQDKH--LFTVLVQE 161

  Fly   198 IKNAF-------RSANLMLSLTV---LPNVNSTWYFDVPKLHPQFDYINLAAFDFLTPLRNPEEA 252
            ::.||       ....||::..|   :.|:.|.  :::|:|....|||::..:|    |....|.
Human   162 MREAFEQEAKQINKPRLMVTAAVAAGISNIQSG--YEIPQLSQYLDYIHVMTYD----LHGSWEG 220

  Fly   253 DFT---APIF-FQDEQNRLPHLNVEFQINYWLQNHCPGQKLNLGIASYGRAWKLSKGSGLS-GAP 312
             :|   :|:: :..:.....:|||::.:|||..|..|.:||.:|..:||..:.||..|... |||
Human   221 -YTGENSPLYKYPTDTGSNAYLNVDYVMNYWKDNGAPAEKLIVGFPTYGHNFILSNPSNTGIGAP 284

  Fly   313 IVHETCGVAPGGIQIQSAEGLLSWPEICSKLSQNASAQYRGELAPLRKVTDLTQKY-GNYALRPA 376
                |.|..|.|...:.: |:.::.|||:.|...|:   :|..||    .::...| ||
Human   285 ----TSGAGPAGPYAKES-GIWAYYEICTFLKNGAT---QGWDAP----QEVPYAYQGN------ 331

  Fly   377 DDNGDFGVWLSFDDPDFAGIKAVYAKGKGLGGIALFDLSYDDFRG-LCTGQKYPILRSIKYFMG 439
                   ||:.:|:.....|||.:.|....||..::.:..|||.| .|...|:|::.::|..:|
Human   332 -------VWVGYDNIKSFDIKAQWLKHNKFGGAMVWAIDLDDFTGTFCNQGKFPLISTLKKALG 388

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.