DRSC/TRiP Functional Genomics Resources

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Protein Alignment Idgf1 and CHIA

DIOPT Version :10

Sequence 1:NP_477258.1 Gene:Idgf1 / 34978 FlyBaseID:FBgn0020416 Length:439 Species:Drosophila melanogaster
Sequence 2:NP_970615.2 Gene:CHIA / 27159 HGNCID:17432 Length:476 Species:Homo sapiens


Alignment Length:454 Identity:128/454 - (28%)
Similarity:208/454 - (45%) Gaps:86/454 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 QLFYILGLLSVTSL-THAASNLICYYDSNSYLRQGLAKMHTNELDLALQFCTHLVYGYAGLKSGT 67
            :|..:.||:.:.:| ..:|..|.||:.:.:..|.||.:...:.:|..|  ||||:|.:||.::..
Human     3 KLILLTGLVLILNLQLGSAYQLTCYFTNWAQYRPGLGRFMPDNIDPCL--CTHLIYAFAGRQNNE 65

  Fly    68 LELFSLNVDLDMFYYKDITALRQKFPQLKILLSVGGDRDVDEAHPNKYVELLEANRTAQQNFIDS 132
            :.....|   |:..|:....|:.|..|||.||::|| .:...|.....|...| ||   |.||.|
Human    66 ITTIEWN---DVTLYQAFNGLKNKNSQLKTLLAIGG-WNFGTAPFTAMVSTPE-NR---QTFITS 122

  Fly   133 SMILLKRNGFDGLDLAFQLPRNKPRKVHGSLGSYWKSFKKLFTGDFVVDPQAEEHKSQFTDLVGN 197
            .:..|::..|||||..::.|        ||.||                |..::|  .||.||..
Human   123 VIKFLRQYEFDGLDFDWEYP--------GSRGS----------------PPQDKH--LFTVLVQE 161

  Fly   198 IKNAF-------RSANLMLSLTV---LPNVNSTWYFDVPKLHPQFDYINLAAFDFLTPLRNPEEA 252
            ::.||       ....||::..|   :.|:.|.  :::|:|....|||::..:|    |....|.
Human   162 MREAFEQEAKQINKPRLMVTAAVAAGISNIQSG--YEIPQLSQYLDYIHVMTYD----LHGSWEG 220

  Fly   253 DFT---APIF-FQDEQNRLPHLNVEFQINYWLQNHCPGQKLNLGIASYGRAWKLSKGSGLS-GAP 312
             :|   :|:: :..:.....:|||::.:|||..|..|.:||.:|..:||..:.||..|... |||
Human   221 -YTGENSPLYKYPTDTGSNAYLNVDYVMNYWKDNGAPAEKLIVGFPTYGHNFILSNPSNTGIGAP 284

  Fly   313 IVHETCGVAPGGIQIQSAEGLLSWPEICSKLSQNASAQYRGELAPLRKVTDLTQKY-GNYALRPA 376
                |.|..|.|...:.: |:.::.|||:.|...|:   :|..||    .::...| ||      
Human   285 ----TSGAGPAGPYAKES-GIWAYYEICTFLKNGAT---QGWDAP----QEVPYAYQGN------ 331

  Fly   377 DDNGDFGVWLSFDDPDFAGIKAVYAKGKGLGGIALFDLSYDDFRG-LCTGQKYPILRSIKYFMG 439
                   ||:.:|:.....|||.:.|....||..::.:..|||.| .|...|:|::.::|..:|
Human   332 -------VWVGYDNIKSFDIKAQWLKHNKFGGAMVWAIDLDDFTGTFCNQGKFPLISTLKKALG 388

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Idgf1NP_477258.1 GH18_IDGF 23..438 CDD:119352 122/431 (28%)
CHIANP_970615.2 GH18_chitolectin_chitotriosidase 24..387 CDD:119351 122/430 (28%)
ChtBD2 429..476 CDD:214696
Blue background indicates that the domain is not in the aligned region.

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