DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf1 and lmd-5

DIOPT Version :9

Sequence 1:	NP_477258.1	Gene:	Idgf1 / 34978	FlyBaseID:	FBgn0020416	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_001309512.1	Gene:	lmd-5 / 187942	WormBaseID:	WBGene00020141	Length:	1518	Species:	Caenorhabditis elegans

Alignment Length:	474	Identity:	93/474 - (19%)
Similarity:	166/474 - (35%)	Gaps:	158/474 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 TSLTHAAS---NLICYYDSNSYLRQGLAKMHTNELDLALQFCTHLVYGYAGL-KSGTLELFSLNV 75
            :|...|||   .::.||..     .|..::..|:    |:..||:::.:..: ..|:::...::.
Worm   980 SSSVPAASCGKRIVGYYTG-----WGEREITENQ----LKKLTHVIFAFVAMYADGSVKFGPVSA 1035

  Fly    76 D--------------LDMFYYKDITALRQKFPQLKILLSVGG-DRDVDEAHPNKYVELLEANRTA 125
            |              :||  .|...|:..   .:::|.:||| |.       ::|...:.|:...
Worm  1036 DDPGPQAGKKAERRFVDM--KKKARAVNS---GVRVLFAVGGWDN-------SQYFSSVAADSGK 1088

  Fly   126 QQNFIDSSMILLKRNGFDGLDLAFQLPRNKPRKVHGSLGSYWKSFKKLFTGDFVVDPQAEEHKSQ 190
            ::||:||....::.:..||:||.::.|..|                   .||          |..
Worm  1089 RRNFVDSVASFIEHHKIDGVDLDWEYPEMK-------------------GGD----------KQN 1124

  Fly   191 FTDLVGNIKNAFRSANLMLS--------LTVLPNVNSTWY----FDVPKLHPQFDYINLAAFDFL 243
            ...|:..::..|   |.|.|        |..|.:....|.    :|:..:....|:||:..:|:.
Worm  1125 HVTLIRELRERF---NGMASRNNRKDPYLITLASAAGEWNLREGYDLKGILNYADFINVMTYDYY 1186

  Fly   244 ------------TPLRNPEEADFTAPIFFQDEQNRLPHLNVEFQINYWLQNHCPGQKLNLGIASY 296
                        ||          ||::|...:.....||.:|.:.::..|.....:|.:|:..|
Worm  1187 GAWESKWGAYTGTP----------APLYFGSLKGFSGKLNADFSMKFYACNTKKPSQLTMGVPFY 1241

  Fly   297 GRAWK-------LSKGSGLSGAPIVHETCGVAPGGIQIQSAE---GLLSWPEICSKLSQNASAQY 351
            ||.||       .|.....:.||               |:.:   |.:.|..:..:.....||.:
Worm  1242 GRYWKNVLEPIDASDNMWRTAAP---------------QNGKYEGGYVGWRNLEKEGWNKGSATW 1291

  Fly   352 RGELAPLRKVTDLTQKYGNYALRPADDNGDFGVWLSFDDPDFAGIKAVYAKGKGLGGIALFDLSY 416
                   .|.|.          .|...|....::|.|::......|..||..:.|||:.::.|..
Worm  1292 -------HKKTK----------TPYIMNNGARMFLGFENERSLKEKMDYATNRNLGGLMIWALDL 1339

  Fly   417 DD----------FRGLCTG 425
            ||          ..|||:|
Worm  1340 DDDADTLLNLVSSAGLCSG 1358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf1	NP_477258.1	GH18_IDGF	23..438	CDD:119352	89/463 (19%)
Idgf1	NP_477258.1	Glyco_18	24..417	CDD:214753	83/442 (19%)
lmd-5	NP_001309512.1	LysM	22..65	CDD:197609
		LysM	77..120	CDD:197609
		LysM	151..194	CDD:197609
		LysM	220..260	CDD:197609
		LysM	275..312	CDD:197609
		LysM	386..429	CDD:197609
		Self-incomp_S1	851..944	CDD:283566
		Glyco_18	991..1336	CDD:214753	82/439 (19%)
		GH18_chitinase-like	992..1336	CDD:299167	82/438 (19%)
		ChtBD1_GH18_2	1388..1435	CDD:211315
		ChtBD1_GH18_2	1462..1513	CDD:211315
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164461
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.700