DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf1 and cht-1

DIOPT Version :9

Sequence 1:	NP_477258.1	Gene:	Idgf1 / 34978	FlyBaseID:	FBgn0020416	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_508588.1	Gene:	cht-1 / 180628	WormBaseID:	WBGene00000503	Length:	617	Species:	Caenorhabditis elegans

Alignment Length:	440	Identity:	111/440 - (25%)
Similarity:	183/440 - (41%)	Gaps:	98/440 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 CYYDSNSYLRQGLAKMHTNELDLALQFCTHLVYGYAGLKSG-TLELFSLNVDLDMFY-----YKD 84
            ||:.:.:..|||.||....:....|  |||:::.:..:.:. |:..:. ..||...:     |:.
Worm    57 CYFTNWAQYRQGRAKFVPEDYTPGL--CTHILFAFGWMNADYTVRAYD-PADLPNDWAGEGMYRR 118

  Fly    85 ITALRQKFPQLKILLSVGGDRDVDEAHPNKYVELLEANRTAQQNFIDSSMILLKRNGFDGLDLAF 149
            :..|:....|||.|||.||     .:......:.:.|:..:::.||||::..::..||||:|:.:
Worm   119 VNKLKVTDTQLKTLLSFGG-----WSFGTALFQGMAASSASRKVFIDSAITFVRTWGFDGIDIDW 178

  Fly   150 QLPRNKPRKVHGSLGSYWKSFKKLFTGDFVVDPQAEEHKSQFTDLVGNIKNAFRSA-------NL 207
            :.                              |......:.:..||..:|.|..|.       .|
Worm   179 EY------------------------------PSGATDMANYVALVKELKAACESEAGSTGKDRL 213

  Fly   208 MLSLTVL--PNVNSTWYFDVPKLHPQFDYINLAAFDFLTPLRNPEEADFTAPIFFQDEQNRLP-- 268
            :::..|.  |......| |:|.|.|.||:|.|.::||.....:  ...|.:|::...|   ||
Worm   214 LVTAAVAAGPATIDAGY-DIPNLAPNFDFILLMSYDFFGAWAS--LVGFNSPLYATTE---LPAE 272

  Fly   269 --HLNVEFQINYWLQNHCPGQKLNLGIASYGRAWKLSKGS----GLSGAPIVHETCGVAPGGIQI 327
              ..||:....||.|...|.:|:.:|:.:|||.|.|:..|    |.||:|        |.....:
Worm   273 WNGWNVDSSARYWNQKGMPKEKIIVGMPTYGRGWTLNNASAINPGTSGSP--------AKITQYV 329

  Fly   328 QSAEGLLSWPEICSKLSQNASAQYRGELAPLRKVTDLTQKYGNYALRPADDNGDFGVWLSFDDPD 392
            |.| |:.::.|.|..|:..|:..:..:    .:|..|.|  ||.             |.|:||.:
Worm   330 QEA-GVGAYFEFCEMLANGATRYWDSQ----SQVPYLVQ--GNQ-------------WWSYDDEE 374

  Fly   393 FAGIKAVYAKGKGLGGIALFDLSYDDFRGLCT---GQKYPILRSIKYFMG 439
            ....|..|.|.:|.||..::.|.:|||...|:   ||.||::..|...:|
Worm   375 SFANKMAYVKREGYGGAFVWTLDFDDFNAGCSNSNGQLYPLISVIAKELG 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf1	NP_477258.1	GH18_IDGF	23..438	CDD:119352	110/437 (25%)
Idgf1	NP_477258.1	Glyco_18	24..417	CDD:214753	101/413 (24%)
cht-1	NP_508588.1	GH18_chitolectin_chitotriosidase	55..423	CDD:119351	110/437 (25%)
		Glyco_18	57..399	CDD:214753	101/413 (24%)
		CBM_14	481..532	CDD:279884
		CBM_14	567..615	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810