DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf1 and lmd-4

DIOPT Version :9

Sequence 1:	NP_477258.1	Gene:	Idgf1 / 34978	FlyBaseID:	FBgn0020416	Length:	439	Species:	Drosophila melanogaster
Sequence 2:	NP_504862.2	Gene:	lmd-4 / 179121	WormBaseID:	WBGene00017233	Length:	2011	Species:	Caenorhabditis elegans

Alignment Length:	430	Identity:	80/430 - (18%)
Similarity:	156/430 - (36%)	Gaps:	130/430 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 LQFCTHLVYGYAGL-KSGTLELFSLNVD---------LDMFYYKDITALRQKFPQLKILLSVGG- 103
            |:..||:::.:..: :.|:::..:::.|         .:..:.......|.....:::|.:|||
Worm  1498 LKKLTHVIFAFVAMYEDGSVKFGAVSEDDSGPQAAKKAERRFLNMKKKARAANSGVRVLFAVGGW 1562

  Fly   104 DRDVDEAHPNKYVELLEANRTAQQNFIDSSMILLKRNGFDGLDLAFQLP--RNKPRKVHGSLGSY 166
            |.       ::|...:.|:...::.|:||....::....||:||.::.|  ..|..|.|..|
Worm  1563 DN-------SQYFSSVAADSGKRKKFVDSIASFVEDQKIDGVDLDWEYPDSNGKDAKNHVQL--- 1617

  Fly   167 WKSFKKLFTGDFVVDPQAEEHKSQFTDLVGNIKNAFRSANLMLSLTVLPNVNSTWY----FDVPK 227
                             .:|.:.:|:::.   |...|....:::|.   :....|.    :|:..
Worm  1618 -----------------IKEIREKFSEMA---KKKKRKDPYVITLA---SAAGEWNLRKGYDLKG 1659

  Fly   228 LHPQFDYINLAAFDFL------------TPLRNPEEADFTAPIFFQDEQNRLPHLNVEFQINYWL 280
            :....|:||:..:|:.            ||          ||::|...:.....||.:|.:.::.
Worm  1660 ILKYADFINVMTYDYYGAWESKWGAYTGTP----------APLYFGSLKGFSGKLNADFSMKFYA 1714

  Fly   281 QNHCPGQK---LNLGIASYGRAWK-----LSKGSGL--SGAPIVHETCGVAPGGIQIQSAE---G 332
               |..:|   ||:|:..|||.||     :.|...:  :.||               |:.:   |
Worm  1715 ---CKTEKPSQLNMGVPFYGRYWKNVLGPIDKSDNMWRTAAP---------------QNGKYEGG 1761

  Fly   333 LLSWPEICSKLSQNASAQYRGELAPLRKVTDLTQKYGNYALRPADDNGDFGVWLSFDDPDFAGIK 397
            .:.|..:..:.....||.:..:                 ...|...|.....:|.|::......|
Worm  1762 YVGWRNLAKEGWNKGSASWHEK-----------------TKTPYIMNNGAKKFLGFENERSLKEK 1809

  Fly   398 AVYAKGKGLGGIALFDLSYDD----------FRGLCTGQK 427
            ..||..:.|||:.::.|..||          ..|||:|.|
Worm  1810 MKYATDRNLGGLMIWALDLDDDADTLLNLVSSAGLCSGGK 1849

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf1	NP_477258.1	GH18_IDGF	23..438	CDD:119352	80/430 (19%)
Idgf1	NP_477258.1	Glyco_18	24..417	CDD:214753	73/408 (18%)
lmd-4	NP_504862.2	LysM	25..65	CDD:197609
		LysM	79..120	CDD:197609
		LysM	142..185	CDD:197609
		LysM	209..250	CDD:197609
		LysM	270..313	CDD:197609
		LysM	334..377	CDD:197609
		LysM	401..444	CDD:197609
		LysM	469..509	CDD:197609
		LysM	550..590	CDD:197609
		LysM	635..678	CDD:197609
		LysM	710..750	CDD:197609
		LysM	760..802	CDD:197609
		LysM	876..919	CDD:197609
		Self-incomp_S1	1359..1433	CDD:283566
		Glyco_18	1480..1825	CDD:214753	72/404 (18%)
		GH18_chitinase-like	1481..1824	CDD:299167	72/403 (18%)
		ChtBD1_GH18_2	1873..1924	CDD:211315
		ChtBD1_GH18_2	1951..2002	CDD:211315
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164462
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.700