Protein Alignment CaBP1 and PDI1

DIOPT Version :10

• Sequence 1: NP_609792.1
• Gene: CaBP1 / 34976
• FlyBaseID: FBgn0025678
• Length: 433
• Species: Drosophila melanogaster
• Sequence 2: NP_009887.1
• Gene: PDI1 / 850314
• SGDID: S000000548
• Length: 522
• Species: Saccharomyces cerevisiae
• Alignment Length: 499
• Identity: 98/499 - (19%)
• Similarity: 153/499 - (30%)
• Gaps: 223/499 - (44%)

  Fly     6 SILLLAFVVGSVSAFYSPSD-GVVELTPSNFDREVLKDDAIWVVEFYAPWCGHCQSLVPEYKKLA 69
            |.||||..|.:.....:|.| .||:|...:|:..:...|.: :.||:|||||||:::.|||.|.|
Yeast    12 SSLLLASSVFAQQEAVAPEDSAVVKLATDSFNEYIQSHDLV-LAEFFAPWCGHCKNMAPEYVKAA 75

  Fly    70 KAL-KGVVKVGSVNADADSTLSGQFGVRGFPTIKIF-GANKKSPTDYNGQRTAKAIAE------- 125
            :.| :..:.:..::...:..|..:..:.|||::||| .::..:..||.|.|||:||.:
Yeast    76 ETLVEKNITLAQIDCTENQDLCMEHNIPGFPSLKIFKNSDVNNSIDYEGPRTAEAIVQFMIKQSQ 140

  Fly   126 ----------AALA--------------------------------------------------- 129
                      |.||
Yeast   141 PAVAVVADLPAYLANETFVTPVIVQSGKIDADFNATFYSMANKHFNDYDFVSAENADDDFKLSIY 205

  Fly   130 ----------------------------------------------------------------- 129
                                                                             
Yeast   206 LPSAMDEPVVYNGKKADIADADVFEKWLQVEALPYFGEIDGSVFAQYVESGLPLGYLFYNDEEEL 270

  Fly   130 --------EVKKKVQGVLGGGG------GSSSGGSGSSSG------DDVIE--------LTEDNF 166
                    |:.||.:|::....      |..:|.......      .|:.|        |:|:.|
Yeast   271 EEYKPLFTELAKKNRGLMNFVSIDARKFGRHAGNLNMKEQFPLFAIHDMTEDLKYGLPQLSEEAF 335

  Fly   167 DKL-------------------------VLNSDDIW--------------------------LVE 180
            |:|                         ::.|.:|:                          ||.
Yeast   336 DELSDKIVLESKAIESLVKDFLKGDASPIVKSQEIFENQDSSVFQLVGKNHDEIVNDPKKDVLVL 400

  Fly   181 FFAPWCGHCKNLAP---EWAKAAKELKGKVKLGALDATAHQSKAAEYNVRGYPTIKFFPAGSKRA 242
            ::||||||||.|||   |.|.........|.:..||.|.:..:...  :.|||||..:|.|.|
Yeast   401 YYAPWCGHCKRLAPTYQELADTYANATSDVLIAKLDHTENDVRGVV--IEGYPTIVLYPGGKK-- 461

  Fly   243 SDAQEYDGGRTASDIVSWASDKHVANVPAPELIEIINESTFETA 286
            |::..|.|.|:...:..:..:....:|....|.|...|...|.|
Yeast   462 SESVVYQGSRSLDSLFDFIKENGHFDVDGKALYEEAQEKAAEEA 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CaBP1	NP_609792.1	PDI_a_P5	26..119	CDD:239299	30/94 (32%)
		PDI_a_P5	157..262	CDD:239299	40/166 (24%)
		P5_C	271..400	CDD:239281	5/16 (31%)
PDI1	NP_009887.1	ER_PDI_fam	32..492	CDD:273457	85/464 (18%)