DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CaBP1 and PDIL2-2

DIOPT Version :9

Sequence 1:	NP_001285979.1	Gene:	CaBP1 / 34976	FlyBaseID:	FBgn0025678	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_171990.3	Gene:	PDIL2-2 / 839355	AraportID:	AT1G04980	Length:	447	Species:	Arabidopsis thaliana

Alignment Length:	437	Identity:	183/437 - (41%)
Similarity:	264/437 - (60%)	Gaps:	19/437 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LASILLLAFVVGSVSAFYSPSDGVVELTPSNFDREVLKDDAIWVVEFYAPWCGHCQSLVPEYKKL 68
            :..:|...|..|  :|.|..|..|::||||||..:||..:.:.:|||:||||||||||.|.::|:
plant    13 ICCLLFALFDRG--NALYGSSSPVLQLTPSNFKSKVLNSNGVVLVEFFAPWCGHCQSLTPTWEKV 75

  Fly    69 AKALKGVVKVGSVNADADSTLSGQFGVRGFPTIKIFGANKKSPTDYNGQRTAKAIAEAALAEVKK 133
            |..|||:..|.:::|||..::|..:|||||||||:| ...|.|.||.|.|.||:|::.|:.::|.
plant    76 ASTLKGIATVAAIDADAHKSVSQDYGVRGFPTIKVF-VPGKPPIDYQGARDAKSISQFAIKQIKA 139

  Fly   134 --------KVQGVLGGGGGSSSGGSGSSSGDDVIELTEDNFDKLVLNSDDIWLVEFFAPWCGHCK 190
                    |..|...|||.|....|..|:.   :||...|||:||..|.::|:||||||||||||
plant   140 LLKDRLDGKTSGTKNGGGSSEKKKSEPSAS---VELNSSNFDELVTESKELWIVEFFAPWCGHCK 201

  Fly   191 NLAPEWAKAAKELKGKVKLGALDATAHQSKAAEYNVRGYPTIKFFPAGSKRASDAQEYDGGRTAS 255
            .|||||.|||..||||||||.::..|.||..:.:.|:|:|||..|  ||.::|.. .|:|.|:||
plant   202 KLAPEWKKAANNLKGKVKLGHVNCDAEQSIKSRFKVQGFPTILVF--GSDKSSPV-PYEGARSAS 263

  Fly   256 DIVSWASDKHVANVPAPELIEIINESTFETACEGKPLCVVSVLPHILDCDAKCRNKFLDTLRTLG 320
            .|.|:|.::..:|....|:.|:......|..|....:|.||.||.|||..|:.|||:|:.|.::.
plant   264 AIESFALEQLESNAGPAEVTELTGPDVMEDKCGSAAICFVSFLPDILDSKAEGRNKYLEMLLSVA 328

  Fly   321 EKFKQKQWGWAWAEGGQQLALEESLEVGGFGYPAMAVVNFKKMKFSVLKGSFSKDGINEFLRDIS 385
            :|||:..:|:.|...|:|..||:.:.|||:|||||..:|.||..::.||..|....:.:|:::.:
plant   329 DKFKKDPYGFVWVAAGKQPDLEKRVGVGGYGYPAMVALNAKKGAYAPLKSGFEVKHLKDFVKEAA 393

  Fly   386 YGRGHTAPVRGAKKPAIVSVDPWDGKDGQLPTEEDIDLSDIDLDKDE 432
            .|.....|:.|..:  ||..:.||||||::...::..|.|:..:.||
plant   394 KGGKGNLPIDGTME--IVKTEAWDGKDGEVVDADEFSLEDLMGNDDE 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaBP1	NP_001285979.1	PDI_a_P5	26..119	CDD:239299	48/92 (52%)
		PDI_a_P5	157..262	CDD:239299	56/104 (54%)
		Thioredoxin_6	190..383	CDD:290560	80/192 (42%)
		P5_C	271..400	CDD:239281	45/128 (35%)
PDIL2-2	NP_171990.3	PDI_a_P5	33..134	CDD:239299	52/101 (51%)
		PDI_a_P5	168..270	CDD:239299	56/107 (52%)
		Thioredoxin_6	201..391	CDD:290560	80/192 (42%)
		P5_C	279..408	CDD:239281	45/130 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	121	1.000	Domainoid score	I1865
eggNOG	1	0.900	-	-		E2759_KOG0191
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4198
Inparanoid	1	1.050	349	1.000	Inparanoid score	I621
OMA	1	1.010	-	-		QHG58248
OrthoDB	1	1.010	-	-		D840943at2759
OrthoFinder	1	1.000	-	-		FOG0000934
OrthoInspector	1	1.000	-	-		otm2773
orthoMCL	1	0.900	-	-		OOG6_100473
Panther	1	1.100	-	-	LDO	PTHR45815
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1799
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840