DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaBP1 and Tmx3

DIOPT Version :9

Sequence 1:	NP_001285979.1	Gene:	CaBP1 / 34976	FlyBaseID:	FBgn0025678	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	XP_038953303.1	Gene:	Tmx3 / 682967	RGDID:	1592777	Length:	470	Species:	Rattus norvegicus

Alignment Length:	287	Identity:	81/287 - (28%)
Similarity:	123/287 - (42%)	Gaps:	82/287 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   156 DDVIELTEDNFDKLVLNSDDIWLVEFFAPWCGHCKNLAPEWAKAAKELK---GKVKLGALDATAH 217
            :|:.|..:||      ..||||||:|:||||||||.|.|.|.:...|:|   ..||:|.:|||::
  Rat    46 EDLNESFKDN------RKDDIWLVDFYAPWCGHCKKLEPIWNEVGLEMKSIGSPVKVGKMDATSY 104

  Fly   218 QSKAAEYNVRGYPTIKFFPAGSKRASDAQEYDGGRTASDIVSWA---SDKHVANVPAPELIEIIN 279
            .|.|:|:.||||||||..     :...|..|.|.||..||:.:|   |...:..:|:.::.:.:.
  Rat   105 SSIASEFGVRGYPTIKLL-----KGDLAYNYRGPRTKDDIIEFAHRVSGALIRPLPSQQMFDHVR 164

  Fly   280 E--STFETACEGK-PLCVVSVLPHILDCDAKCRNKFLDTLR--------------------TLGE 321
            :  ..|.....|: ||                :.|::|...                    ||.|
  Rat   165 KRHRVFFVYIGGESPL----------------KEKYIDAASELIVYTYFFSASEDVVPEYVTLKE 213

  Fly   322 K-----FKQKQW------------GWAWAEGGQQ-LALEESL--EVGGFG-YPAMAVVNFK--KM 363
            .     ||...:            .|...|..|. |.::..|  |:|..| ..|:||::.|  .:
  Rat   214 MPAVLVFKDDTYFVYDEYEDGDLSSWISRERFQNYLTMDGFLLYELGDTGKLVAIAVIDEKNTSL 278

  Fly   364 KFSVLKG---SFSKDGINEFLRDISYG 387
            :.:.||.   ..::|..:.|.||..:|
  Rat   279 EHTRLKSIIQEVARDFRDHFHRDFQFG 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaBP1	NP_001285979.1	PDI_a_P5	26..119	CDD:239299
		PDI_a_P5	157..262	CDD:239299	49/110 (45%)
		Thioredoxin_6	190..383	CDD:290560	60/247 (24%)
		P5_C	271..400	CDD:239281	30/166 (18%)
Tmx3	XP_038953303.1	PDI_a_TMX3	44..147	CDD:239298	49/111 (44%)
Tmx3	XP_038953303.1	ER_PDI_fam	46..>361	CDD:273457	81/287 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910