DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaBP1 and dnajc10

DIOPT Version :9

Sequence 1:	NP_001285979.1	Gene:	CaBP1 / 34976	FlyBaseID:	FBgn0025678	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_001077016.1	Gene:	dnajc10 / 557858	ZFINID:	ZDB-GENE-070327-1	Length:	791	Species:	Danio rerio

Alignment Length:	271	Identity:	80/271 - (29%)
Similarity:	132/271 - (48%)	Gaps:	47/271 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 VVELTPSNFDREV--LKDDAIWVVEFYAPWCGHCQSLVPEYKKLAKALKGVVKVGSVNADADSTL 89
            ||.|.|.:|...|  .|....|:|:|||||||.||:|:||::::|:.|.|:|.||:|:.....:.
Zfish   554 VVTLGPESFQELVKRRKSSETWMVDFYAPWCGPCQALLPEWRRMARMLSGIVNVGTVDCQKHHSF 618

  Fly    90 SGQFGVRGFPTIKIFGAN---KKSPTDYNG-QRTAKAIAEAALAEVKKKVQGVLGGGGGSSSGGS 150
            .....||.:|.|::|..|   :.....||| .|.|.::...||:.:.:.
Zfish   619 CQSESVRAYPEIRLFPQNSNRRDQYQTYNGWHRDAFSLKAWALSSLPRA---------------- 667

  Fly   151 GSSSGDDVIELTEDNFDKLVLNSDDIWLVEFFAPWCGHCKNLAPEWAKAAKELKGKVKLGALDAT 215
                   .::|:.::|.:.||...|.|:::|:|||||.|:..|||:...|:.:||.|:.|.:|..
Zfish   668 -------SVDLSPEDFKRKVLGGKDHWVLDFYAPWCGPCQQFAPEFEVLARMMKGTVRAGKVDCQ 725

  Fly   216 AHQSKAAEYNVRGYPTIKFFPA-GSKRASDAQEYDGGRTASDIVSWASDKHVANVPAPELIEIIN 279
            ||........::.|||::|:|. |:.|.....|:...|.|:.|.                 :|:.
Zfish   726 AHYQTCQSAGIKAYPTVRFYPTLGTTRRDQGGEHINSRDATVIA-----------------DILR 773

  Fly   280 ESTFETACEGK 290
            :...:.|.:||
Zfish   774 QRLQQLALQGK 784

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaBP1	NP_001285979.1	PDI_a_P5	26..119	CDD:239299	37/97 (38%)
		PDI_a_P5	157..262	CDD:239299	35/105 (33%)
		Thioredoxin_6	190..383	CDD:290560	26/102 (25%)
		P5_C	271..400	CDD:239281	4/20 (20%)
dnajc10	NP_001077016.1	DnaJ	33..>129	CDD:223560
		DnaJ	33..95	CDD:278647
		PDI_a_ERdj5_N	128..228	CDD:239301
		ER_PDI_fam	129..648	CDD:273457	35/93 (38%)
		Thioredoxin_like	<276..318	CDD:294274
		PDI_a_family	348..443	CDD:239259
		PDI_a_ERdj5_C	450..546	CDD:239302
		PDI_a_ERdj5_C	552..660	CDD:239302	39/105 (37%)
		PDI_a_ERdj5_C	666..772	CDD:239302	35/145 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0191
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2193
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.840