DRSC/TRiP Functional Genomics Resources

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Protein Alignment CaBP1 and pdia3

DIOPT Version :9

Sequence 1:NP_001285979.1 Gene:CaBP1 / 34976 FlyBaseID:FBgn0025678 Length:433 Species:Drosophila melanogaster
Sequence 2:NP_001186666.1 Gene:pdia3 / 378851 ZFINID:ZDB-GENE-031002-9 Length:494 Species:Danio rerio


Alignment Length:479 Identity:111/479 - (23%)
Similarity:164/479 - (34%) Gaps:234/479 - (48%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 LASILLLAFVVGSVSAFYSPSDGVVELTPSNFDREVLKDDAIWVVEFYAPWCGHCQSLVPEYKKL 68
            ||.:.|:||     :|....|| |:|.|..:||..:...|.| :|||:|||||||:.|.|||:..
Zfish     3 LALLFLVAF-----AAAARASD-VLEYTDDDFDSRIGDHDLI-LVEFFAPWCGHCKRLAPEYEAA 60

  Fly    69 AKALKGVVKVGSVNADADSTLSGQFGVRGFPTIKIFGANKKSPTDYNGQRTAKAI-------AEA 126
            |..|||:|.:..|:..|:|.:.|::||.|:||:|||...:.| ..|:|.|||..|       |..
Zfish    61 ATRLKGIVPLAKVDCTANSKVCGKYGVSGYPTLKIFRDGEDS-GGYDGPRTADGIVSHLKKQAGP 124

  Fly   127 ALAEVKKK-------------VQGVLGGGGGSSSG------------------------------ 148
            |..|:|.:             |.|....||.::.|                              
Zfish   125 ASVELKNEADFEKYIGDRDASVVGFFADGGSAAQGEFLKAASALRESYRFAHTNNEDLLKKHGID 189

  Fly   149 GSG---------SSSGDD--------------------------VIELTEDNFDKL--------- 169
            |.|         |:..:|                          ...:||||.|:|         
Zfish   190 GEGIILFRSPQLSNKFEDSSVLFTEDKFTSAKIKKFIQDNIFGICAHMTEDNKDQLKGKDLLVAY 254

  Fly   170 ----------------------------------------------------------------- 169
                                                                             
Zfish   255 YDVDYEKNPKGSNYWRNRVMKVAKGFLDQGKKLSFAVANKNRFSHDVSELGLDGSSGELPLVGIR 319

  Fly   170 -----------------------------------------------------------VLNSD- 174
                                                                       ::|.| 
Zfish   320 TAKGDKYVMKEEFSRDGKALERFLQDYFDGNLKRYLKSEPVPENNDGPVKVLVAENFDSIVNDDS 384

  Fly   175 -DIWLVEFFAPWCGHCKNLAPEWAKAAKELK--GKVKLGALDATAHQSKAAEYNVRGYPTIKFFP 236
             |: |:||:||||||||:|.|::.:..::|.  ..:.:..:||||: ...:.|.|.|:|||.|.|
Zfish   385 KDV-LIEFYAPWCGHCKSLEPKYKELGEKLSEDPNIVIAKMDATAN-DVPSPYEVSGFPTIYFSP 447

  Fly   237 AGSKRASDAQEYDGGRTASDIVSW 260
            ||.|:  :.::|:|||..||.:|:
Zfish   448 AGRKQ--NPKKYEGGREVSDFISY 469

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CaBP1NP_001285979.1 PDI_a_P5 26..119 CDD:239299 41/92 (45%)
PDI_a_P5 157..262 CDD:239299 46/267 (17%)
Thioredoxin_6 190..383 CDD:290560 26/73 (36%)
P5_C 271..400 CDD:239281
pdia3NP_001186666.1 ER_PDI_fam 18..475 CDD:273457 105/459 (23%)
Thioredoxin_like 19..116 CDD:294274 46/99 (46%)
PDI_b_ERp57 125..230 CDD:239367 12/104 (12%)
PDI_b'_ERp72_ERp57 234..347 CDD:239371 6/112 (5%)
PDI_a_PDI_a'_C 367..470 CDD:239293 39/107 (36%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.910

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