DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaBP1 and CG9302

DIOPT Version :9

Sequence 1:	NP_001285979.1	Gene:	CaBP1 / 34976	FlyBaseID:	FBgn0025678	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_609645.2	Gene:	CG9302 / 34750	FlyBaseID:	FBgn0032514	Length:	510	Species:	Drosophila melanogaster

Alignment Length:	392	Identity:	104/392 - (26%)
Similarity:	155/392 - (39%)	Gaps:	95/392 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 SNFDREVLKDDAIWVVEFYAPWCGHCQSLVPEYKKLAKALKG----VVKVGSVNADADSTLSGQF 93
            ::|.:.:.||....:|.||.||||.|:.:.|||.|.:..||.    ::...:|....::.:...|
  Fly   152 ASFTKHLRKDIRPMLVMFYVPWCGFCKKMKPEYGKASTELKTKGGYILAAMNVERQENAPIRKMF 216

  Fly    94 GVRGFPTIKIFGANKKSPTDYNGQRTAKAIAEAALAEVKKKVQGVLGGGGGSSSGGSGSSSGDDV 158
            .:.||||: |:..|.|....|.|:...:|:....|....|...       ........:.:..::
  Fly   217 NITGFPTL-IYFENGKLRFTYEGENNKEALVSFMLNPNAKPTP-------KPKEPEWSADTNSEI 273

  Fly   159 IELTEDNFDKLVLNSDDIWLVEFFAPWCGHCKNLAPEWAKAAKELKGKV---KLGALDATAHQSK 220
            :.||...|:. .|..:...||.|:||||||||.:.||:.|||.|:|.|.   .|.|||||...|.
  Fly   274 VHLTSQGFEP-ALKDEKSALVMFYAPWCGHCKRMKPEYEKAALEMKQKKIPGLLAALDATKEPSI 337

  Fly   221 AAEYNVRGYPTIKFFPAGSKRASDAQEYD-GGRTASDIVSWASD-KHVANVPAPEL--------- 274
            |.:|.|:||||:|||..|      ..::: ..|.||.||.:..| |.....|.||.
  Fly   338 AEKYKVKGYPTVKFFSNG------VFKFEVNVREASKIVEFMRDPKEPPPPPPPEKSWEEEEDSK 396

  Fly   275 -IEIINESTFETACEGK---------PLC------------VVSVL---PHI----LDCDAKCRN 310
             :..:::..|.:..:.|         |.|            ..:.|   |.|    :||
  Fly   397 EVLFLDDDNFSSTLKRKKHALVMFYAPWCGHCKHTKPEFTAAATALQDDPRIAFVAIDC------ 455

  Fly   311 KFLDTLRTLGEKFKQKQWGWAWAEGGQQLALEESLEVGGFGYPAMAVVNFKKMKFSVLKGSFSKD 375
               ..|..|..|:..:                        |||.:...::.|.|.....|..|||
  Fly   456 ---TKLAALCAKYNVR------------------------GYPTILYFSYLKTKLDYNGGRTSKD 493

  Fly   376 GI 377
            .|
  Fly   494 FI 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaBP1	NP_001285979.1	PDI_a_P5	26..119	CDD:239299	28/89 (31%)
		PDI_a_P5	157..262	CDD:239299	46/108 (43%)
		Thioredoxin_6	190..383	CDD:290560	59/231 (26%)
		P5_C	271..400	CDD:239281	24/145 (17%)
CG9302	NP_609645.2	PDI_b_PDIR_N	24..131	CDD:239365
		PDI_a_PDIR	144..249	CDD:239295	29/97 (30%)
		ER_PDI_fam	166..500	CDD:273457	101/378 (27%)
		PDI_a_PDIR	272..373	CDD:239295	46/107 (43%)
		PDI_a_PDIR	397..498	CDD:239295	22/132 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463735
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0191
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740