DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaBP1 and Erp27

DIOPT Version :9

Sequence 1:	NP_001285979.1	Gene:	CaBP1 / 34976	FlyBaseID:	FBgn0025678	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_001100095.1	Gene:	Erp27 / 297698	RGDID:	1565381	Length:	272	Species:	Rattus norvegicus

Alignment Length:	145	Identity:	31/145 - (21%)
Similarity:	58/145 - (40%)	Gaps:	37/145 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 SDGVVELTPSNFDREVLKDDAIWVVEFYAPWCG----------HCQSLV----PE-------YKK 67
            ::.:.:|..:...|.:..::..||.| |:|..|          |...::    ||       |:|
  Rat   121 AEDIDDLDAAKLSRFIHLNNLHWVTE-YSPMIGAGLFNTMVQTHLLLIMNKASPEYEESLRSYQK 184

  Fly    68 LAKALKGVVKVGSVNADADSTLSGQ----FGVR--GFPTIKIFGANKKSPTDYNGQRTAKAIAEA 126
            .||..:|  ::..|..|:....:|:    |.::  ..|.:.|:    :|..|   :..|..|.|.
  Rat   185 AAKLFQG--QILFVLVDSGKRENGKVIAYFRLKESQLPALAIY----ESVDD---KWDALTITEV 240

  Fly   127 ALAEVKKKVQGVLGG 141
            .:.:|:....|.|.|
  Rat   241 TVEKVQSFCNGFLKG 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaBP1	NP_001285979.1	PDI_a_P5	26..119	CDD:239299	24/119 (20%)
		PDI_a_P5	157..262	CDD:239299
		Thioredoxin_6	190..383	CDD:290560
		P5_C	271..400	CDD:239281
Erp27	NP_001100095.1	PDI_b_family	43..139	CDD:239279	2/17 (12%)
		Thioredoxin_6	64..250	CDD:290560	28/138 (20%)
		PDI_b'_family	156..253	CDD:239280	21/105 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0191
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900