DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaBP1 and SPAC13F5.05

DIOPT Version :9

Sequence 1:	NP_001285979.1	Gene:	CaBP1 / 34976	FlyBaseID:	FBgn0025678	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_593653.1	Gene:	SPAC13F5.05 / 2542841	PomBaseID:	SPAC13F5.05	Length:	363	Species:	Schizosaccharomyces pombe

Alignment Length:	412	Identity:	101/412 - (24%)
Similarity:	168/412 - (40%)	Gaps:	112/412 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LASILLLAFVVGSVSAFYSPSDG--VVELTPSNFDREVLKDDAIWVVEFYAPWCGHCQSLVPEYK 66
            ||...|::.|.|     |||..|  .:||...|| |:.:|.....:|.|||||||:|:.|||.|:
pombe    13 LACFSLVSGVFG-----YSPMFGSNTIELNSKNF-RKFVKAKGPSLVVFYAPWCGYCKKLVPTYQ 71

  Fly    67 KLAKALKGVVKVGSVNADADS--TLSGQFGVRGFPTIKIFGANKK----SPTDYNGQRTAKAIAE 125
            |||..|..::.|.:|:.|||.  .:..|:.|:||||||:...:.|    |.|||||.|:.|::.:
pombe    72 KLASNLHSLLPVTAVDCDADQNRAVCSQYQVQGFPTIKLVYPSSKGSSLSSTDYNGDRSYKSLQK 136

  Fly   126 AALAEVKKKVQGVLGGGGGSSSGGSGSSSGDDVIELTED--NFDKLVLNSDDIWLVEFFAPWCGH 188
            .....:..||: :|             :|.....:..:|  |..|::|.|..:.....:
pombe   137 FVSDSIPSKVK-IL-------------TSEAKTQKFIQDAQNSSKVILISQKMKPTLLY------ 181

  Fly   189 CKNLAPEWAKAAKELKGKVKLGALDATAHQSKAAEYNVRGYPTIKFFPA--------GSKRASDA 245
             |:|:.|::        .:....:.|.|:.:..  :|:..|......|.        |:...|::
pombe   182 -KSLSNEFS--------SLPFSFMPAKANVNDL--FNISAYVDTSDLPILFIKHPNNGTSFFSNS 235

  Fly   246 QEYDGGRTASDIVSWASDKHVANVPAPELIEIINESTFE----TACEGKPLCVVSVLPHILD--C 304
            ...|      .||.:             |...|.::.|.    |.| .|..|::::.....|  .
pombe   236 LNRD------SIVEF-------------LQSSIKDNNFSEYLATFC-SKKSCIITIQDKDSDSGI 280

  Fly   305 DAKCRNKF-------LDTLRTLGEKFKQKQWGWAWAEGGQQLALEESLEVGGFGYPAMAVVNFKK 362
            |...|.|:       |....|:.|:                  ||::|::   ||....:::.||
pombe   281 DESIRKKYPKLHFVRLGRNTTVAER------------------LEDTLDL---GYSDTFLLSLKK 324

  Fly   363 MKFSVLKGSFSKDGINEFLRDI 384
            ..::.  ..:.|. :..:|.||
pombe   325 SHYNA--KPYGKP-LRRWLEDI 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaBP1	NP_001285979.1	PDI_a_P5	26..119	CDD:239299	44/100 (44%)
		PDI_a_P5	157..262	CDD:239299	18/114 (16%)
		Thioredoxin_6	190..383	CDD:290560	36/213 (17%)
		P5_C	271..400	CDD:239281	25/127 (20%)
SPAC13F5.05	NP_593653.1	PDI_a_MPD1_like	32..139	CDD:239300	45/107 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	83	1.000	Domainoid score	I2248
eggNOG	1	0.900	-	-		E2759_KOG0191
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000934
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100473
Panther	1	1.100	-	-	LDO	PTHR45815
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2193
SonicParanoid	1	1.000	-	-		X1799
TreeFam	0	0.000	Not matched by this tool.
	8	7.840