DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaBP1 and SPAC17H9.14c

DIOPT Version :9

Sequence 1:	NP_001285979.1	Gene:	CaBP1 / 34976	FlyBaseID:	FBgn0025678	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_593584.1	Gene:	SPAC17H9.14c / 2542270	PomBaseID:	SPAC17H9.14c	Length:	359	Species:	Schizosaccharomyces pombe

Alignment Length:	346	Identity:	103/346 - (29%)
Similarity:	159/346 - (45%)	Gaps:	61/346 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LLAFVVGSVSAFYSPSDGVVELTPSN-FDREVLKDDAIWVVEFYAPWCGHCQSLVPEYKKLAKAL 72
            ||:||:.::.|....| |||||...| .:..:.......::||||.|||||:||.|.|::|....
pombe     5 LLSFVIFALFALVFAS-GVVELQSLNELENTIRASKKGALIEFYATWCGHCKSLAPVYEELGALF 68

  Fly    73 K--GVVKVGSVNADADSTLSGQFGVRGFPTIKIFGANKKSPTDYNGQRTAKAIAEAALAEV---K 132
            :  ..|.:|.::||..|.::.::.:.||||:..|..:...|..|:..|...::.:....:.   |
pombe    69 EDHNDVLIGKIDADTHSDVADKYHITGFPTLIWFPPDGSEPVQYSNARDVDSLTQFVSEKTGIKK 133

  Fly   133 KKVQGVLGGGGGSSSGGSGSSSGDDVIELTEDNFDKLVLNSDDIWLVEFFAPWCGHCKNLAPEWA 197
            :|:  ||               ..:|:||...||||:|::.....||||:|.|||:||.|||.:.
pombe   134 RKI--VL---------------PSNVVELDSLNFDKVVMDDKKDVLVEFYADWCGYCKRLAPTYE 181

  Fly   198 KAAKELKGK--VKLGALDATAHQSKAAEYNVRGYPTIKFFPAGSKRASDAQE-YDGGRTASDIVS 259
            ...|..|.:  |::..::|.........:.|..:|||||||...|   |..| |:|.|:..
pombe   182 TLGKVFKNEPNVEIVKINADVFADIGRLHEVASFPTIKFFPKDDK---DKPELYEGDRSLE---- 239

  Fly   260 WASDKHVANVPAPELIEIIN-ESTFETACEGKPLCVVSVLPHILDCDAKCRNKFLDTLRTLGEKF 323
                         .|||.|| :|..:.:.:|..|.....:|...:..|    :|||......|..
pombe   240 -------------SLIEYINKKSGTQRSPDGTLLSTAGRIPTFDEFAA----EFLDMSNAAKEVV 287

  Fly   324 KQKQWGWAWAEGGQQLALEES 344
            .:|.         :|||||:|
pombe   288 LEKV---------KQLALEDS 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaBP1	NP_001285979.1	PDI_a_P5	26..119	CDD:239299	32/95 (34%)
		PDI_a_P5	157..262	CDD:239299	39/107 (36%)
		Thioredoxin_6	190..383	CDD:290560	43/159 (27%)
		P5_C	271..400	CDD:239281	21/75 (28%)
SPAC17H9.14c	NP_593584.1	PDI_a_ERp38	21..125	CDD:239296	33/103 (32%)
		Thioredoxin_6	55..247	CDD:290560	65/228 (29%)
		PDI_a_ERp38	141..245	CDD:239296	42/123 (34%)
		ERp29	265..354	CDD:285048	13/48 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0191
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000934
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100473
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1799
TreeFam	1	0.960	-	-
	6	5.670