Protein Alignment CaBP1 and PDILT

DIOPT Version :10

• Sequence 1: NP_609792.1
• Gene: CaBP1 / 34976
• FlyBaseID: FBgn0025678
• Length: 433
• Species: Drosophila melanogaster
• Sequence 2: NP_777584.1
• Gene: PDILT / 204474
• HGNCID: 27338
• Length: 584
• Species: Homo sapiens
• Alignment Length: 299
• Identity: 66/299 - (22%)
• Similarity: 117/299 - (39%)
• Gaps: 63/299 - (21%)

  Fly    61 LVPEYKKLAKALKGVVKVGSVNADADSTLSGQ----FGVR--GFPTIKIFG----ANKKSPTDYN 115
            ::..||..:|..:.  |:..:..|||...:|:    |.|.  ..|:::|..    |..|.|:|..
Human   292 IIQHYKLASKEFQN--KILFILVDADEPRNGRVFKYFRVTEVDIPSVQILNLSSDARYKMPSDDI 354

  Fly   116 GQRTAKAIAEAALAEVKKKVQGVLGGGGGSSSGGSGSSSGDD---------VIELTEDNFDKLVL 171
            ...:.|....:.|::...|.|                 |.::         |.:|...||:.:|.
Human   355 TYESLKKFGRSFLSKNATKHQ-----------------SSEEIPKYWDQGLVKQLVGKNFNVVVF 402

  Fly   172 NSDDIWLVEFFAPWCGHCKNLAPEWAKAAKELK--GKVKLGALDATAHQSKAAEYNVRGYPTIKF 234
            :.:....|.|:|||...||.|.|...:..::.:  ..:.:..:|.||:..:.. |..| ||..:.
Human   403 DKEKDVFVMFYAPWSKKCKMLFPLLEELGRKYQNHSTIIIAKIDVTANDIQLM-YLDR-YPFFRL 465

  Fly   235 FPAGSKRASDAQEYDGGRTA---SDIVSWASDKHVA-------NVPAPELIEIINESTFETACEG 289
            ||:||::   |..|.|..|.   ||.:    :.|:.       .:.:.|..|:|.|   |...|.
Human   466 FPSGSQQ---AVLYKGEHTLKGFSDFL----ESHIKTKIEDEDELLSVEQNEVIEE---EVLAEE 520

  Fly   290 KPLCVV-SVLPHILDCDAKCRNKFLDTLRTLGEKFKQKQ 327
            |.:.:: ..||.....:.:...|::..|.....|.|..:
Human   521 KEVPMMRKGLPEQQSPELENMTKYVSKLEEPAGKKKTSE 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CaBP1	NP_609792.1	PDI_a_P5	26..119	CDD:239299	16/67 (24%)
		PDI_a_P5	157..262	CDD:239299	31/118 (26%)
		P5_C	271..400	CDD:239281	13/58 (22%)
PDILT	NP_777584.1	ER_PDI_fam	46..501	CDD:273457	53/236 (22%)
		Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138	581..584