DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaBP1 and dnj-27

DIOPT Version :9

Sequence 1:	NP_001285979.1	Gene:	CaBP1 / 34976	FlyBaseID:	FBgn0025678	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_001040704.1	Gene:	dnj-27 / 173065	WormBaseID:	WBGene00001045	Length:	788	Species:	Caenorhabditis elegans

Alignment Length:	251	Identity:	78/251 - (31%)
Similarity:	119/251 - (47%)	Gaps:	45/251 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LLAFVVGSVSAFYSPSDGVVELTPSNFDREVL--KDDAIWVVEFYAPWCGHCQSLVPEYKKLAKA 71
            :|.|:..|:    :||  |:|::|..|:..|:  ||:..|:|:|:|||||.||.|.||.:|.|:.
Worm   539 ILEFLDNSL----NPS--VMEMSPEQFEELVMNRKDEETWLVDFFAPWCGPCQQLAPELQKAARQ 597

  Fly    72 LKGV---VKVGSVNADADSTLSGQFGVRGFPTIKIFGANK-----KSP-TDYNGQ--RTAKAIAE 125
            :...   ..|.|::....:.......:..:||::::.|.|     :|| .||...  |.:.:|
Worm   598 IAAFDENAHVASIDCQKYAQFCTNTQINSYPTVRMYPAKKTKQPRRSPFYDYPNHMWRNSDSI-- 660

  Fly   126 AALAEVKKKVQGVLGGGGGSSSGGSGSSSGDDVIELTEDNFDKLVLNSDDIWLVEFFAPWCGHCK 190
                  ::.|...|               ..:|:.|..| |...||:|.:.|:|:|||||||||.
Worm   661 ------QRWVYNFL---------------PTEVVSLGND-FHTTVLDSSEPWIVDFFAPWCGHCI 703

  Fly   191 NLAPEWAKAAKELKGKVKLGALDATAHQSKAAEYNVRGYPTIKFF--PAGSKRASD 244
            ..||.:.:.||||.|||....:|............||.||||:.:  ..|..|..|
Worm   704 QFAPIYDQIAKELAGKVNFAKIDCDQWPGVCQGAQVRAYPTIRLYTGKTGWSRQGD 759

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaBP1	NP_001285979.1	PDI_a_P5	26..119	CDD:239299	32/105 (30%)
		PDI_a_P5	157..262	CDD:239299	37/90 (41%)
		Thioredoxin_6	190..383	CDD:290560	19/57 (33%)
		P5_C	271..400	CDD:239281
dnj-27	NP_001040704.1	DnaJ	18..>150	CDD:223560
		DnaJ	20..82	CDD:278647
		PDI_a_ERdj5_N	116..214	CDD:239301
		Thioredoxin_like	222..>312	CDD:294274
		ER_PDI_fam	438..750	CDD:273457	75/240 (31%)
		PDI_a_ERdj5_C	438..543	CDD:239302	1/3 (33%)
		PDI_a_ERdj5_C	549..664	CDD:239302	36/124 (29%)
		PDI_a_ERdj5_C	670..773	CDD:239302	37/91 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2193
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940