DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CaBP1 and png-1

DIOPT Version :9

Sequence 1:	NP_001285979.1	Gene:	CaBP1 / 34976	FlyBaseID:	FBgn0025678	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_492913.1	Gene:	png-1 / 173028	WormBaseID:	WBGene00010160	Length:	606	Species:	Caenorhabditis elegans

Alignment Length:	227	Identity:	42/227 - (18%)
Similarity:	78/227 - (34%)	Gaps:	76/227 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   156 DDVIELTEDNFDKLVLNSDDIWLVEFFAPWCGHCKNLAPEWAKAAKELKGKVKLGALDATAHQSK 220
            ::::|.::.|  :|:       :::|||.|||.|:.::|.:.:.:.|. |......::....:..
Worm    13 NNILERSDAN--RLI-------IIDFFANWCGPCRMISPIFEQFSAEY-GNATFLKVNCDVARDI 67

  Fly   221 AAEYNVRGYPTIKFF----------------------------PAGSKRASDAQEYDGGRTASDI 257
            ...||:...||..|.                            ||....|||:::    |.....
Worm    68 VQRYNISAMPTFIFLKNRQQVDMVRGANQQAIAEKIRQHYSPTPANPNAASDSEK----RFLEQF 128

  Fly   258 VSWASDKHVANVP---APELIEIINESTFETACEGK-----PLCVVSVLPHIL------------ 302
            |.      .:|||   ..|:.:.:..|.......|:     |....::|..:|
Worm   129 VK------CSNVPRSYQDEVFKALARSVMPEELVGRAMTEGPRDEKAILKDLLHWFKTQFFTWFD 187

  Fly   303 -----DCDAKCRNKFLDTLRTLGEKFKQKQWG 329
                 .|..||..   |.|:....:.:||:.|
Worm   188 RPTCPKCTLKCST---DGLQGTPTREEQKEGG 216

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaBP1	NP_001285979.1	PDI_a_P5	26..119	CDD:239299
		PDI_a_P5	157..262	CDD:239299	25/132 (19%)
		Thioredoxin_6	190..383	CDD:290560	32/193 (17%)
		P5_C	271..400	CDD:239281	14/81 (17%)
png-1	NP_492913.1	TRX_family	20..103	CDD:239245	17/92 (18%)
		Transglut_core	204..296	CDD:280085	3/13 (23%)
		YebA	<235..312	CDD:224224
		PAW	407..604	CDD:299187
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910