DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaBP1 and ZK973.11

DIOPT Version :9

Sequence 1:	NP_001285979.1	Gene:	CaBP1 / 34976	FlyBaseID:	FBgn0025678	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_491361.1	Gene:	ZK973.11 / 172039	WormBaseID:	WBGene00022836	Length:	447	Species:	Caenorhabditis elegans

Alignment Length:	287	Identity:	74/287 - (25%)
Similarity:	113/287 - (39%)	Gaps:	87/287 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   158 VIELTEDNFDKLVLNSDDIWLVEFFAPWCGHCKNLAPEWAKAAKELKGK---VKLGALDATAHQS 219
            |::|::...|   :..:.:|.|||:||||.|||.|.|.|.:....|...   :::|.||.|...:
Worm    30 VLDLSDKFLD---VKDEGMWFVEFYAPWCAHCKRLHPVWDQVGHTLSDSNLPIRVGKLDCTRFPA 91

  Fly   220 KAAEYNVRGYPTIKFFPAGSKRASDAQEYDGGRTASDIVSWASDKHVANVPAPELIEIINESTFE 284
            .|.:.:::|||||.||     |.....:|.|||....:||:|  |..|   || :||:|||:..|
Worm    92 VANKLSIQGYPTILFF-----RNGHVIDYRGGREKEALVSFA--KRCA---AP-IIEVINENQIE 145

  Fly   285 ---TACEGKPLCV--------------------------VSVLPHILDCDAKCRNK--------- 311
               .:...:|..|                          .||.|.  :.||..|.:
Worm   146 KVKLSARSQPSYVFFGTSSGPLFDAFNEAASSKFSVARFYSVAPP--ENDASFRQRVAVFKDNFE 208

  Fly   312 --FLDTLRTLGEKFKQKQWGWAWAEGGQQLALEESLEVGGFGYPAMAVVNFKKMKFSVLKGSFSK 374
              |...:..|.|...:::|     .|..|.......|:|..|...:.||:.:..||:
Worm   209 IEFNGDIEKLTEWVTRERW-----PGFLQATSSNLAEIGASGKLVVLVVSSESHKFN-------- 260

  Fly   375 DGINEFLRDISYGRGHTAPVRGAKKPA 401
                           :|:|:|...|.|
Worm   261 ---------------NTSPIREFHKTA 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaBP1	NP_001285979.1	PDI_a_P5	26..119	CDD:239299
		PDI_a_P5	157..262	CDD:239299	37/106 (35%)
		Thioredoxin_6	190..383	CDD:290560	56/235 (24%)
		P5_C	271..400	CDD:239281	32/168 (19%)
ZK973.11	NP_491361.1	ER_PDI_fam	29..>348	CDD:273457	74/287 (26%)
ZK973.11	NP_491361.1	PDI_a_TMX3	29..132	CDD:239298	39/111 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910