Protein Alignment CG4278 and NIF3L1

DIOPT Version :9

• Sequence 1: NP_609790.1
• Gene: CG4278 / 34970
• FlyBaseID: FBgn0014092
• Length: 292
• Species: Drosophila melanogaster
• Sequence 2: NP_001129511.1
• Gene: NIF3L1 / 60491
• HGNCID: 13390
• Length: 377
• Species: Homo sapiens
• Alignment Length: 348
• Identity: 118/348 - (33%)
• Similarity: 179/348 - (51%)
• Gaps: 88/348 - (25%)

  Fly    13 LAAVVKELENFAPTSWAEKWDNVGLLIEPHREKQIKKILLTNDLTEPVVKEALEKEAELIISYHP 77
            |.|::..|.:||..|:||.|||||||:||.....:..:.|||||||.|::|.|:|:|:||:||||
Human    30 LKALLSSLNDFASLSFAESWDNVGLLVEPSPPHTVNTLFLTNDLTEEVMEEVLQKKADLILSYHP 94

  Fly    78 PIFKPLTRITQSHWKERVVAACLANDIALYSPHTAWDKKSGGVNDWLSKAVNIISIRPLEPE--- 139
            |||:|:.|||.:.||||:|...|.|.:.:||||||:|....|||:||:|.:...:.||:.|.
Human    95 PIFRPMKRITWNTWKERLVIRALENRVGIYSPHTAYDAAPQGVNNWLAKGLGACTSRPIHPSKAP 159

  Fly   140 -----------------------LGAPPG------------------------------------ 145
                                   :.|..|
Human   160 NYPTEGNHRVEFNVNYTQDLDKVMSAVKGIDGVSVTSFSARTGNEEQTRINLNCTQKALMQVVDF 224

  Fly   146 -----------------------TGSGRY--IETKMELSQVVESLQKRIRNS-VHVALAVGHTPK 184
                                   ||.||.  ::..:.|:.:::.:::.::.| :.:||.||.|.:
Human   225 LSRNKQLYQKTEILSLEKPLLLHTGMGRLCTLDESVSLATMIDRIKRHLKLSHIRLALGVGRTLE 289

  Fly   185 TLIQSVGICAGSGASLLKGIQADLIITGEMSHHEVLEFTHNNTTVLLCNHSNSERGFLHEFCPIL 249
            :.::.|.:|||||:|:|:|::|||.:|||||||:.|:.......|:||.|||:|||||.:...:|
Human   290 SQVKVVALCAGSGSSVLQGVEADLYLTGEMSHHDTLDAASQGINVILCEHSNTERGFLSDLRDML 354

  Fly   250 AKSLNEECLVFVSEVDKDPLVTV 272
            ...|..:..:.:||.|:|||..|
Human   355 DSHLENKINIILSETDRDPLQVV 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4278	NP_609790.1	NIF3	16..251	CDD:280036	108/322 (34%)
NIF3L1	NP_001129511.1	NIF3	33..354	CDD:307756	107/320 (33%)
		Mediates interaction with COPS2. /evidence=ECO:0000250|UniProtKB:Q9EQ80	244..377		50/132 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160165
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0327
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5881
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54155
OrthoDB	1	1.010	-	-		D1293706at2759
OrthoFinder	1	1.000	-	-		FOG0005738
OrthoInspector	1	1.000	-	-		oto90581
orthoMCL	1	0.900	-	-		OOG6_102764
Panther	1	1.100	-	-	LDO	PTHR13799
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R811
SonicParanoid	1	1.000	-	-		X4727
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	13	12.790