Protein Alignment cact and Nfkb1

DIOPT Version :10

• Sequence 1: NP_476942.1
• Gene: cact / 34969
• FlyBaseID: FBgn0000250
• Length: 500
• Species: Drosophila melanogaster
• Sequence 2: XP_063138698.1
• Gene: Nfkb1 / 81736
• RGDID: 70498
• Length: 1015
• Species: Rattus norvegicus
• Alignment Length: 480
• Identity: 112/480 - (23%)
• Similarity: 192/480 - (40%)
• Gaps: 134/480 - (27%)

  Fly    35 AANPSSSLATSGKIGG------KTQDQTAAINKQKEFAVPNETSDSGFISGPQ--SSQIFSEEIV 91
            |.:|.::.:.:|...|      |.:.:..|.:..:|...|.|....|  .||.  .:...:|.|.
  Rat   418 AFHPGATKSNTGITHGTINTKFKNEPRDCAKSDDREILNPPEKETQG--EGPSLFMASTKTEAIA 480

  Fly    92 PDSEEQDKDQQESAPQKEQPVVLDSGIIDEEEDQEEQEKEEEHQDTT---TATADSMRLKHSADT 153
            |.|..:||::             |.|..|....::..:..:.|.:..   ..|.|...|
  Rat   481 PASTMEDKEE-------------DVGFQDNLFLEKALQLAKRHANALFDYAVTGDVKML------ 526

  Fly   154 GIPQWTVESHLVSRGEQLNNLGQSSSTQITGRSKVQSSTASTANANPSGSGATSSAPPSSINIMN 218
                ..|:.||.:
  Rat   527 ----LAVQRHLTA---------------------------------------------------- 535

  Fly   219 AWEQFYQQNDDGDTPLHLACISGSVDVVAALIRMAPHPC---LLNIQNDVAQTPLHLAALTAQPN 280
                  .|:::||:.||||.|.....:|..|:.:.....   ::|::||:.|||||||.:|.|.:
  Rat   536 ------VQDENGDSVLHLAIIHLHAQLVRDLLEVTSGSISDDIINMRNDLYQTPLHLAVITKQED 594

  Fly   281 IMRILLLAGAEPTVRDRHGNTALHLSCIAGEKQCVRALTEKFGATEIHEAHRQYGHRSNDKAVSS 345
            ::..||..||:.::.||.||:.|||:...|..:.:..|.:                  |.||...
  Rat   595 VVEDLLRVGADLSLLDRWGNSVLHLAAKEGHDKILGVLLK------------------NSKAALL 641

  Fly   346 LSYACLPADLEIRNYDGERCVHLAAEAGHIDILRILVSHGADINAREGKSGRTPLHIAIEGCNED 410
            :::.         |.:|...:|:|..:..:..|::||:.||::||:|.|||||.||:|:|..|..
  Rat   642 INHP---------NGEGLNAIHIAVMSNSLSCLQLLVAAGAEVNAQEQKSGRTALHLAVEYDNIS 697

  Fly   411 LANFLLDECEKLNLETATYAGLTAYQFACIMNKSRMQNILEKRGAETVTPPDSDYDSSDIEDLDD 475
            ||..||.|.:.| :::.||.|.|....|.....:|:..:|:..||:.:..     :...:.||||
  Rat   698 LAGCLLLEGDAL-VDSTTYDGTTPLHIAAGRGSTRLAALLKAAGADPLVE-----NFEPLYDLDD 756

  Fly   476 TKMYDRFGDPRYFVSYNGGNPMTVA 500
            :  :::.|:....|.  |..|:.:|
  Rat   757 S--WEKAGEDEGVVP--GTTPLDMA 777

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cact	NP_476942.1	ANKYR	<225..464	CDD:440430	75/241 (31%)
		ANK repeat	229..263	CDD:293786	10/36 (28%)
		ANK repeat	265..296	CDD:293786	13/30 (43%)
		ANK repeat	298..324	CDD:293786	7/25 (28%)
		ANK repeat	361..393	CDD:293786	10/31 (32%)
		ANK repeat	395..425	CDD:293786	15/29 (52%)
Nfkb1	XP_063138698.1	None