DRSC/TRiP Functional Genomics Resources

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Protein Alignment cact and Nfkbib

DIOPT Version :9

Sequence 1:NP_001260496.1 Gene:cact / 34969 FlyBaseID:FBgn0000250 Length:500 Species:Drosophila melanogaster
Sequence 2:NP_001293151.1 Gene:Nfkbib / 18036 MGIID:104752 Length:359 Species:Mus musculus


Alignment Length:315 Identity:90/315 - (28%)
Similarity:132/315 - (41%) Gaps:45/315 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly   198 ANPSGSGATSSAPPSSINIMNAWEQ--FYQQNDDGDTPLHLACISGSVDVVAALIRMAPHPCLLN 260
            |.|.|.|..:...|..     :|..  |....:||||.||||.|......:..|:..:.....|:
Mouse    29 AAPGGPGLGAELGPEL-----SWAPLVFGYVTEDGDTALHLAVIHQHEPFLDFLLGFSAGTEYLD 88

  Fly   261 IQNDVAQTPLHLAALTAQPNIMRILLLAGAEPTVRDRHGNTALHLSCIAGEKQCVRALTEKFGAT 325
            :|||:.||.|||||:..:.:.:..|..|||...|.:|.|:|||||:|......|...|.:. ..:
Mouse    89 LQNDLGQTALHLAAILGEASTVEKLYAAGAGVLVAERGGHTALHLACRVRAHTCACVLLQP-RPS 152

  Fly   326 EIHEAHRQYGHRSNDKAVSSLSYACLPAD-------------------LEIRNYDGERCVHLAAE 371
            ...:|...|..:|.| .....|:|....|                   ||..||||...:|:|..
Mouse   153 HPRDASDTYLTQSQD-CTPDTSHAPAAVDSQPNPENEEEPRDEDWRLQLEAENYDGHTPLHVAVI 216

  Fly   372 AGHIDILRILVSHGADINAREGKSGRTPLHIAIEGCNEDLANFLL----DECEKLNLETATYAGL 432
            ....:::|:|...|||:|..|...||||||:|:|.....:...||    |...::      |.|.
Mouse   217 HKDAEMVRLLRDAGADLNKPEPTCGRTPLHLAVEAQAASVLELLLKAGADPTARM------YGGR 275

  Fly   433 TAYQFACIMNKSRMQNILEKRGA-------ETVTPPDSDYDSSDIEDLDDTKMYD 480
            |....|.:.....:..:|...||       :.::|..|....||.::.|:...||
Mouse   276 TPLGSALLRPNPILARLLRAHGAPEPEDEDDKLSPCSSSGSDSDSDNRDEGDEYD 330

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
cactNP_001260496.1 ANK <225..286 CDD:238125 21/60 (35%)
ANK repeat 229..263 CDD:293786 11/33 (33%)
Ank_4 230..286 CDD:290365 20/55 (36%)
ANK 260..416 CDD:238125 55/174 (32%)
ANK repeat 265..296 CDD:293786 12/30 (40%)
Ank_2 270..391 CDD:289560 41/139 (29%)
ANK repeat 298..324 CDD:293786 9/25 (36%)
ANK repeat 361..393 CDD:293786 10/31 (32%)
Ank_5 381..438 CDD:290568 20/60 (33%)
ANK repeat 395..425 CDD:293786 11/33 (33%)
NfkbibNP_001293151.1 ANK 53..226 CDD:238125 52/174 (30%)
ANK repeat 57..91 CDD:293786 11/33 (33%)
ANK 1 57..86 10/28 (36%)
Ank_4 58..113 CDD:290365 20/54 (37%)
ANK repeat 93..124 CDD:293786 12/30 (40%)
ANK 2 93..122 11/28 (39%)
Ank_2 98..234 CDD:289560 40/137 (29%)
ANK 3 126..155 9/29 (31%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 153..194 7/41 (17%)
ANK 202..>298 CDD:238125 29/101 (29%)
ANK repeat 206..237 CDD:293786 10/30 (33%)
ANK 4 206..235 9/28 (32%)
Ank_2 211..298 CDD:289560 25/92 (27%)
ANK repeat 239..271 CDD:293786 11/31 (35%)
ANK 5 240..269 11/28 (39%)
ANK 6 273..302 6/28 (21%)
ANK repeat 273..298 CDD:293786 4/24 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 298..359 8/33 (24%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167846744
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
43.800

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