DRSC/TRiP Functional Genomics Resources

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Protein Alignment cact and Bcl3

DIOPT Version :9

Sequence 1:NP_001260496.1 Gene:cact / 34969 FlyBaseID:FBgn0000250 Length:500 Species:Drosophila melanogaster
Sequence 2:NP_291079.2 Gene:Bcl3 / 12051 MGIID:88140 Length:448 Species:Mus musculus


Alignment Length:234 Identity:75/234 - (32%)
Similarity:121/234 - (51%) Gaps:33/234 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly   227 NDDGDTPLHLACISGSVDVV---AALIRMAPHPCLLNIQNDVAQTPLHLAALTAQPNIMRILLLA 288
            ::|||||||:|.:..::..|   .:|.::....  :::.|::.|||||||.:|..|:::|:|:.|
Mouse   127 DEDGDTPLHIAVVQNNIAAVYRILSLFKLGSRE--VDVHNNLRQTPLHLAVITTLPDMVRLLVTA 189

  Fly   289 GAEPTVRDRHGNTALHLSCIAGEKQCVRALTEKFGATEIHEAHRQYGHRSNDKAVSSLSYACLPA 353
            ||.|...||||.||:||:|......|::||.                    |.|.|.      ..
Mouse   190 GASPMALDRHGQTAIHLACEHRSPSCLQALL--------------------DSATSG------SV 228

  Fly   354 DLEIRNYDGERCVHLAAEAGHIDILRILVSHGADINAREGKSGRTPLHIAIEGCNEDLANFLLDE 418
            |||:|||:|...:|:|...|..:.:.:|:..||||:|.:.||||:||..|:|..:.::...||  
Mouse   229 DLEVRNYEGLTALHVAVNTGCQEAVLLLLERGADIDAVDIKSGRSPLIHAVENNSLNMVQLLL-- 291

  Fly   419 CEKLNLETATYAGLTAYQFACIMNKSRMQNILEKRGAET 457
            ....|:....|:|.:|...|.......:...|.:.||::
Mouse   292 LHGANVNAQMYSGSSALHSASGRGLLPLVRTLVRSGADS 330

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
cactNP_001260496.1 ANK <225..286 CDD:238125 21/61 (34%)
ANK repeat 229..263 CDD:293786 10/36 (28%)
Ank_4 230..286 CDD:290365 20/58 (34%)
ANK 260..416 CDD:238125 55/155 (35%)
ANK repeat 265..296 CDD:293786 15/30 (50%)
Ank_2 270..391 CDD:289560 42/120 (35%)
ANK repeat 298..324 CDD:293786 10/25 (40%)
ANK repeat 361..393 CDD:293786 10/31 (32%)
Ank_5 381..438 CDD:290568 20/56 (36%)
ANK repeat 395..425 CDD:293786 10/29 (34%)
Bcl3NP_291079.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..54
ANK 126..257 CDD:238125 51/157 (32%)
ANK repeat 129..164 CDD:293786 10/36 (28%)
ANK 1 129..161 10/33 (30%)
Ank_5 152..207 CDD:290568 24/56 (43%)
ANK 2 166..195 15/28 (54%)
ANK repeat 168..197 CDD:293786 15/28 (54%)
ANK 195..324 CDD:238125 46/156 (29%)
ANK repeat 199..234 CDD:293786 16/60 (27%)
ANK 3 199..228 13/54 (24%)
Ank_2 204..300 CDD:289560 36/123 (29%)
ANK repeat 236..267 CDD:293786 10/30 (33%)
ANK 4 236..265 9/28 (32%)
ANK repeat 270..301 CDD:293786 10/32 (31%)
ANK 5 270..299 10/30 (33%)
Ank_5 289..344 CDD:290568 10/44 (23%)
ANK 298..>354 CDD:238125 7/33 (21%)
ANK repeat 303..334 CDD:293786 6/28 (21%)
ANK 6 303..332 6/28 (21%)
ANK 7 333..362
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 356..448
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1341288at2759
OrthoFinder 1 1.000 - - FOG0002150
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.920

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