Protein Alignment fzy and AMA1

DIOPT Version :9

• Sequence 1: NP_477501.1
• Gene: fzy / 34968
• FlyBaseID: FBgn0001086
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_011741.5
• Gene: AMA1 / 853140
• SGDID: S000003457
• Length: 593
• Species: Saccharomyces cerevisiae
• Alignment Length: 572
• Identity: 145/572 - (25%)
• Similarity: 235/572 - (41%)
• Gaps: 164/572 - (28%)

  Fly    67 SSEGKTKKSNTTPSKTPGGGDRFIPNRAATN----------FELAH------------------F 103
            :|:...|..|::.:.|.  .|||||...:.|          |::::                  |
Yeast    11 NSKSSNKNINSSGNSTE--VDRFIPKSVSRNAYKSIPMLNGFDISYSELCEKSPSPERLSSPEFF 73

  Fly   104 LVNKDSGD----KSDEENDKATSSNSNESNV----QASAHKGDRQKLISE--------VAQVGDS 152
            ...:::|.    .:..|...::.|:|:||.|    .|.|.:.|..||..|        ...:|..
Yeast    74 NELRNTGHYESISTTNEFSMSSISSSSESQVTRSGSARASRNDYSKLTKEQKDHRKNIAHSLGFQ 138

  Fly   153 KGGRILCYQ---------NKA-------------------------------------PAAPETH 171
            ...|:..::         |||                                     .|:|:..
Yeast   139 LPDRVFTFETTSAEILEKNKAIKNCFGPGSCAEIRSTFDFSTLSPDVARYYIANSNARSASPQRQ 203

  Fly   172 -NNPLKVVYSIKTPISTKSGSRYIPTTSERILDAPDFINDYYLNLMDWS-ADNIVAVALGSCVYL 234
             ..|.|.|.|            :||   .|:||||...||:|.||:.|| ..|.|.|.||..||:
Yeast   204 IQRPAKRVKS------------HIP---YRVLDAPCLRNDFYSNLISWSRTTNNVLVGLGCSVYI 253

  Fly   235 WNAQTGNIEQLTE---FEEGDYAGSLSWIQEGQILAIGNSTGAVELWD---------CSKVKRLR 287
            |:.:.|.:..|..   .|:.|....:|:........:|...|.:.|:|         .::.:.:.
Yeast   254 WSEKEGAVSILDHQYLSEKRDLVTCVSFCPYNTYFIVGTKFGRILLYDQKEFFHSSNTNEKEPVF 318

  Fly   288 VMDGHSAR-VGSLAW------NSFLVSSGSRDGTI-------VHHDVR--AREHKL--------- 327
            |....|.: :..|.|      ..|.|  |..:|.:       :|..::  ::..||
Yeast   319 VFQTESFKGICCLEWFKPGEICKFYV--GEENGNVSLFEIKSLHFPIKNWSKRQKLEDENLIGLK 381

  Fly   328 --STLSGHTQEVCGLKWSTDFKYLASGGNDNLVNVWSAASGGVGTATDPLHKF-NDHQAAVRALA 389
              ||.....|:|||:..:.....||.|||||..::|.     :.....|:.|| ..|:|||:|:|
Yeast   382 LHSTYQAQAQQVCGISLNEHANLLAVGGNDNSCSLWD-----ISDLDKPIKKFVLPHKAAVKAIA 441

  Fly   390 WCPWQPSTLASGGGTADRCIKFWNVNNGTLMKSVDSKSQVCSLLFSRHYKELISAHGFANNQ--- 451
            :|||..|.||:|||:.|||||||:.:.|||:..:.:..||.||::|..:|::::..||.:.:
Yeast   442 FCPWSKSLLATGGGSKDRCIKFWHTSTGTLLDEICTSGQVTSLIWSLRHKQIVATFGFGDTKNPV 506

  Fly   452 -LTIWKYPTMVKQADL-TGHTSRVLQMAMSPDGSTVISAGADETLR---LWN 498
             :|::.||.:.|..:: :.:..|||...:||....:..|..|||:|   |||
Yeast   507 LITLYSYPKLSKLLEVRSPNPLRVLSAVISPSSMAICVATNDETIRFYELWN 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fzy	NP_477501.1	WD40	<208..500	CDD:225201	102/340 (30%)
		WD40	216..498	CDD:238121	95/330 (29%)
		WD40 repeat	256..291	CDD:293791	6/43 (14%)
		WD40 repeat	297..332	CDD:293791	11/60 (18%)
		WD40 repeat	337..373	CDD:293791	11/35 (31%)
		WD40 repeat	386..424	CDD:293791	21/37 (57%)
		WD40 repeat	429..467	CDD:293791	11/42 (26%)
		WD40 repeat	473..513	CDD:293791	12/29 (41%)
AMA1	NP_011741.5	WD40 repeat	234..271	CDD:293791	12/36 (33%)
		WD40	266..561	CDD:421866	85/300 (28%)
		WD40 repeat	276..321	CDD:293791	6/44 (14%)
		WD40 repeat	328..374	CDD:293791	9/47 (19%)
		WD40 repeat	394..432	CDD:293791	13/42 (31%)
		WD40 repeat	437..474	CDD:293791	22/36 (61%)
		WD40 repeat	482..523	CDD:293791	10/40 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346539
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0305
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19918
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840