DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fzy and CDC20.3

DIOPT Version :9

Sequence 1:	NP_477501.1	Gene:	fzy / 34968	FlyBaseID:	FBgn0001086	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_198060.2	Gene:	CDC20.3 / 832766	AraportID:	AT5G27080	Length:	442	Species:	Arabidopsis thaliana

Alignment Length:	436	Identity:	199/436 - (45%)
Similarity:	275/436 - (63%)	Gaps:	40/436 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 DRFIPNRAATNFELAHFLVNKDSGDKSDEENDKATSSNSNESNVQASAHKGDRQKLISEVAQVGD 151
            |||||||:|.:|:.|::.:.:  |.|.:.  |:.||::              |:..::::|.|.:
plant    23 DRFIPNRSAMDFDFANYALTQ--GRKRNV--DEITSAS--------------RKAYMTQLAVVMN 69

  Fly   152 SKGGRILCYQNKAPA------APETHNNPLKVVYSIKTPISTKSGSRYIPTTSERILDAPDFIND 210
            ....|||.::||..|      :...|.||..|           ...||||..|||:||||..::|
plant    70 QNRTRILAFRNKPKALLSSNHSDSPHQNPKSV-----------KPRRYIPQNSERVLDAPGLMDD 123

  Fly   211 YYLNLMDWSADNIVAVALGSCVYLWNAQTGNIEQLTEFEE--GDYAGSLSWIQEGQILAIGNSTG 273
            :||||:||.:.|::|:|||..||||:|.:|:..:|...:|  |... |::|.|:|..||:|....
plant   124 FYLNLLDWGSANVLAIALGDTVYLWDASSGSTSELVTIDEDKGPVT-SINWTQDGLDLAVGLDNS 187

  Fly   274 AVELWDCSKVKRLR-VMDGHSARVGSLAWNSFLVSSGSRDGTIVHHDVRAREHKLSTLSGHTQEV 337
            .|:|||....:::| ::.||.:||||||||:.::::|..||.||::|||.|...:.|..|||:||
plant   188 EVQLWDFVSNRQVRTLIGGHESRVGSLAWNNHILTTGGMDGKIVNNDVRIRSSIVGTYLGHTEEV 252

  Fly   338 CGLKWSTDFKYLASGGNDNLVNVWSAASGGVGTATDP-LHKFNDHQAAVRALAWCPWQPSTLASG 401
            ||||||...|.||||||.|:|::|...|......|.. ||:|.:|.||||||||||:|.:.||:|
plant   253 CGLKWSESGKKLASGGNYNVVHIWDHRSVASSKPTRQWLHRFEEHTAAVRALAWCPFQATLLATG 317

  Fly   402 GGTADRCIKFWNVNNGTLMKSVDSKSQVCSLLFSRHYKELISAHGFANNQLTIWKYPTMVKQADL 466
            ||..|..|||||.:.|..:.||::.|||||||:|:..:||:|:|||..||||:||||:|.|.|:|
plant   318 GGVGDGKIKFWNTHTGACLNSVETGSQVCSLLWSQRERELLSSHGFTQNQLTLWKYPSMSKMAEL 382

  Fly   467 TGHTSRVLQMAMSPDGSTVISAGADETLRLWNCFAPDPLASKKAVS 512
            .|||||||.||.||:|.||.||..||.|||||.|...|..:|||.|
plant   383 NGHTSRVLFMAQSPNGCTVASAAGDENLRLWNVFGEPPKTTKKAAS 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fzy	NP_477501.1	WD40	<208..500	CDD:225201	154/295 (52%)
		WD40	216..498	CDD:238121	147/285 (52%)
		WD40 repeat	256..291	CDD:293791	12/35 (34%)
		WD40 repeat	297..332	CDD:293791	16/34 (47%)
		WD40 repeat	337..373	CDD:293791	18/35 (51%)
		WD40 repeat	386..424	CDD:293791	21/37 (57%)
		WD40 repeat	429..467	CDD:293791	23/37 (62%)
		WD40 repeat	473..513	CDD:293791	24/40 (60%)
CDC20.3	NP_198060.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	103	1.000	Domainoid score	I2251
eggNOG	1	0.900	-	-		E2759_KOG0305
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	391	1.000	Inparanoid score	I496
OMA	1	1.010	-	-		QHG54440
OrthoDB	1	1.010	-	-		D1220675at2759
OrthoFinder	1	1.000	-	-		FOG0000628
OrthoInspector	1	1.000	-	-		otm3270
orthoMCL	1	0.900	-	-		OOG6_101791
Panther	1	1.100	-	-	O	PTHR19918
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1762
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840