Protein Alignment fzy and cdc20

DIOPT Version :10

• Sequence 1: NP_477501.1
• Gene: fzy / 34968
• FlyBaseID: FBgn0001086
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_988945.1
• Gene: cdc20 / 394542
• XenbaseID: XB-GENE-970663
• Length: 507
• Species: Xenopus tropicalis
• Alignment Length: 534
• Identity: 271/534 - (50%)
• Similarity: 350/534 - (65%)
• Gaps: 35/534 - (6%)

  Fly     1 MSQFNFVSDLQNALIMDGE-TRGPAPRWKKKLE----ASLNGSVNT-TRSVLSVSYNTSFSGVQA 59
            |:||.|.:|:.:.|.:|.. |..|..||::|.:    :|||.|.|| |.|.:..| |.|.|..:.
 Frog     1 MAQFAFETDINSILKLDTPITNAPLARWQRKAKEGNCSSLNTSANTSTMSPMKTS-NRSHSSSKT 64

  Fly    60 PTKTPGKSSEGKTKKSNTTPSKTPGGGDRFIPNRAATNFELAHFLVNKDSGDKSDEENDKATSSN 124
            |:||||||.    .|...|||:  .|||||||||:|...::|.||:.|        ||:.|.:|.
 Frog    65 PSKTPGKSG----PKMQGTPSR--AGGDRFIPNRSAMQMDVASFLLCK--------ENEPADTSP 115

  Fly   125 SNESNVQASAHKGDRQKLISEVAQVGDSKGGRILCYQNKAPAAPETHNNPLKVVYSIK-TPISTK 188
            :          |.::||..:......|.:..:||....:...|||.:.|.|||:||.| ||.|:|
 Frog   116 T----------KKEQQKAWAMNLNGFDMEEAKILRLGGRPQNAPEGYQNNLKVLYSQKTTPGSSK 170

  Fly   189 SGSRYIPTTSERILDAPDFINDYYLNLMDWSADNIVAVALGSCVYLWNAQTGNIEQLTEFEEG-D 252
            ...||||:..:|:|||||..|||||||:|||:.|.:||||...|||||..||:|..|.:.|.. :
 Frog   171 KTGRYIPSMPDRVLDAPDIRNDYYLNLIDWSSQNFLAVALNDSVYLWNYATGDIILLLQMEHSEE 235

  Fly   253 YAGSLSWIQEGQILAIGNSTGAVELWDCSKVKRLRVMDGHSARVGSLAWNSFLVSSGSRDGTIVH 317
            |..|:|||:||..||:|.|...|:|||..:.||||.|..||:|||:|:||:.::|||||.|.|.|
 Frog   236 YISSVSWIKEGNYLAVGTSNSEVQLWDVQQQKRLRNMTSHSSRVGALSWNNHILSSGSRTGHIHH 300

  Fly   318 HDVRAREHKLSTLSGHTQEVCGLKWSTDFKYLASGGNDNLVNVWSAASGGVGTATDPLHKFNDHQ 382
            ||||..:|.:|||:||||||||||||.|.:|||||.||||||||....|..|..: |:..|..||
 Frog   301 HDVRVAQHHVSTLTGHTQEVCGLKWSPDGRYLASGANDNLVNVWPCVQGDSGEFS-PVQTFTQHQ 364

  Fly   383 AAVRALAWCPWQPSTLASGGGTADRCIKFWNVNNGTLMKSVDSKSQVCSLLFSRHYKELISAHGF 447
            .||:|:||||||.:.||:||||:||.|:.|||.:||.:.|||:.|||||:|:|.:||||||.|||
 Frog   365 GAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGTCLNSVDTHSQVCSILWSTNYKELISGHGF 429

  Fly   448 ANNQLTIWKYPTMVKQADLTGHTSRVLQMAMSPDGSTVISAGADETLRLWNCFAPDPLASKKAVS 512
            |.|||.:||||||.:..:|.|||:|||.:|:||||.||.||.||||||||.||..||: :||...
 Frog   430 AQNQLVLWKYPTMTRVTELKGHTARVLNLAISPDGCTVASAAADETLRLWKCFEVDPV-TKKEKE 493

  Fly   513 TSKGKQSVFRQSIR 526
            .::..:|:..||||
 Frog   494 KARSSKSIIHQSIR 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fzy	NP_477501.1	WD40	<218..498	CDD:441893	168/280 (60%)
		WD40 repeat	256..291	CDD:293791	19/34 (56%)
		WD40 repeat	297..332	CDD:293791	20/34 (59%)
		WD40 repeat	337..373	CDD:293791	23/35 (66%)
		WD40 repeat	386..424	CDD:293791	22/37 (59%)
		WD40 repeat	429..467	CDD:293791	24/37 (65%)
		WD40 repeat	473..513	CDD:293791	25/39 (64%)
cdc20	NP_988945.1	WD40	<205..479	CDD:441893	164/274 (60%)
		WD40 repeat	237..272	CDD:293791	18/34 (53%)
		WD40 repeat	278..315	CDD:293791	22/36 (61%)
		WD40 repeat	320..361	CDD:293791	24/41 (59%)
		WD40 repeat	368..406	CDD:293791	22/37 (59%)
		WD40 repeat	411..449	CDD:293791	24/37 (65%)