DRSC/TRiP Functional Genomics Resources

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Protein Alignment fzy and cort

DIOPT Version :9

Sequence 1:NP_477501.1 Gene:fzy / 34968 FlyBaseID:FBgn0001086 Length:526 Species:Drosophila melanogaster
Sequence 2:NP_001260144.1 Gene:cort / 33937 FlyBaseID:FBgn0000351 Length:483 Species:Drosophila melanogaster


Alignment Length:537 Identity:120/537 - (22%)
Similarity:192/537 - (35%) Gaps:173/537 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    63 TPGKSSEGKTKKSNTTP----------------SKTPGG------GDRFIPNRAATNFELAHFLV 105
            :|.|:|  |..|.:.||                |.|..|      |:||||||    ||..:...
  Fly    10 SPNKNS--KLDKKSLTPFKKVRRKNWKQEAAYKSDTSKGQEVSYVGERFIPNR----FERENIEF 68

  Fly   106 NKDSGDKSDEENDKATS--------------SNSNES-------NVQASAHKGDRQKLISEVAQV 149
            |.....|..|.:...|.              ||.|.:       ..|.|:.:|.|.:::.     
  Fly    69 NLKYIGKRKERDILETGVTLTASYWRQSGFISNINRTFGIGERRLFQFSSQQGTRSRVVD----- 128

  Fly   150 GDSKGGRILCYQNKAPAAPE--THNNPLKVVYSIKTPISTKSGSRYIPTTSERILDAPDFINDYY 212
            .||......|.....|.|.:  ||..|     .|.:|:                        || 
  Fly   129 NDSADSDWPCNPRARPYAIQNATHEMP-----GICSPV------------------------DY- 163

  Fly   213 LNLMDWSADNIVAVALGSCVYLWNAQTGNIEQLTEFEEGDYAGSLSWIQEGQILAIG---NSTGA 274
             |:||||:..:||::.|..|.||.    |:::.|.....:...||.:..:|:.||||   .:...
  Fly   164 -NMMDWSSGGMVAMSSGQDVMLWR----NLDESTMVFSVESPTSLKYSPDGKHLAIGCMDRNYPV 223

  Fly   275 VELWDCSK-----VKRLRVMDGHSARVGSLAW--NSFLVSSGSRDGTIV-------HHDVRAREH 325
            ::||:...     |...::.......:..:.|  :...|..|::.|.|:       :..::.|||
  Fly   224 LDLWEVRSPTEFLVSYRKLFFKSMGYISCIEWSHDGKEVICGTQCGVIIVLAMPTLNTLMQLREH 288

  Fly   326 KLSTLSGHTQEVCGLKWSTDFKYLASGGNDNLVNVWSAASGGVGTATDPLHKFNDHQAAVRALA- 389
            :      ||  |..:|::...||.||...|..:.::.|.                  ..||.|. 
  Fly   289 R------HT--VKKMKFAPTHKYFASSDTDGKIFIFDAV------------------LKVRLLKL 327

  Fly   390 --------WCPWQPSTLASGGGTADR---CIKFWNVNNGTLMKSV---DSKSQVCSLLFSRHYKE 440
                    |.||....||    .|:|   .|..:|:.....:.|.   |.:..:.:|.:|:...|
  Fly   328 DGRSIVFDWHPWTGEDLA----VAERSPASIFIFNIPRRQFVASYRRRDDRIVIKTLTYSKITGE 388

  Fly   441 LISAHGFANNQL----------TIWKYPTMVKQADLTGHTSR-VLQMAMSPDGSTVISAGADETL 494
            |:.      |.:          .|....::.:..||..|..| .|.:..:|||:.:.:.|.|:|.
  Fly   389 LLV------NVIRRDDADLAVCEILVLASLNRVVDLMSHQDRGTLFLMWNPDGTKIATGGLDDTF 447

  Fly   495 RLWNCFAPDPLASKKAV 511
            .|||.|   |...::|:
  Fly   448 SLWNFF---PTYKREAI 461

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fzyNP_477501.1 WD40 <208..500 CDD:225201 77/334 (23%)
WD40 216..498 CDD:238121 72/324 (22%)
WD40 repeat 256..291 CDD:293791 10/42 (24%)
WD40 repeat 297..332 CDD:293791 8/43 (19%)
WD40 repeat 337..373 CDD:293791 8/35 (23%)
WD40 repeat 386..424 CDD:293791 12/52 (23%)
WD40 repeat 429..467 CDD:293791 7/47 (15%)
WD40 repeat 473..513 CDD:293791 13/39 (33%)
cortNP_001260144.1 WD40 <166..453 CDD:225201 74/326 (23%)
WD40 166..451 CDD:295369 72/324 (22%)
WD40 repeat 201..244 CDD:293791 10/42 (24%)
WD40 repeat 251..287 CDD:293791 5/35 (14%)
WD40 repeat 292..326 CDD:293791 10/51 (20%)
WD40 repeat 334..369 CDD:293791 10/38 (26%)
WD40 repeat 377..419 CDD:293791 7/47 (15%)
WD40 repeat 427..466 CDD:293791 13/38 (34%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0305
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR19918
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
32.910

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