Protein Alignment fzy and Fzr1

DIOPT Version :10

• Sequence 1: NP_477501.1
• Gene: fzy / 34968
• FlyBaseID: FBgn0001086
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001101544.2
• Gene: Fzr1 / 314642
• RGDID: 1308713
• Length: 493
• Species: Rattus norvegicus
• Alignment Length: 489
• Identity: 194/489 - (39%)
• Similarity: 286/489 - (58%)
• Gaps: 52/489 - (10%)

  Fly    57 VQAPTKTPGKSSEGKTKKSNTTPSKTPG-GGDRFIPNRAATNFELAHFLVNKDSGDKSDEENDK- 119
            :|.....|..|...:|.....:|..:|. .||||||:||..|:.:....:|::  :||..:|.|
  Rat    15 IQNENTVPCVSEMRRTLTPANSPVSSPSKHGDRFIPSRAGANWSVNFHRINEN--EKSPSQNRKA 77

  Fly   120 --ATSSNSNESNVQASAHKGDRQKLISEVAQVGDSKGGRILCYQNKAPAAPETHNNPLKVVYSIK 182
              |||.|..:....::..|.:......|..|...::..|:      .|:.|| |........|.|
  Rat    78 KDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRL------QPSTPE-HKGLFTYSLSSK 135

  Fly   183 ---------------TPISTKS---------GSRYIPTTSERILDAPDFINDYYLNLMDWSADNI 223
                           :|:|.||         .:|.|.....::||||:..:|:||||:|||:.|:
  Rat   136 RSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLDAPELQDDFYLNLVDWSSLNV 200

  Fly   224 VAVALGSCVYLWNAQTGNIEQLTEFE-EGDYAGSLSWIQEGQILAIGNSTGAVELWDCSKVKRLR 287
            ::|.||:|||||:|.|..:.:|.:.. |||...|:.|.:.|.::|:|...|.|::||.:..|:|.
  Rat   201 LSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAAGKKLS 265

  Fly   288 VMDGHSARVGSLAWNSFLVSSGSRDGTIVHHDVRA----REHKLSTLSGHTQEVCGLKWSTDFKY 348
            |::||:||||:||||:..:||||||..|:..|:|.    .|.:   |.||.|||||||||||.:.
  Rat   266 VLEGHTARVGALAWNADQLSSGSRDRMILQRDIRTPALQSERR---LQGHRQEVCGLKWSTDHQL 327

  Fly   349 LASGGNDNLVNVWSAASGGVGTATDPLHKFNDHQAAVRALAWCPWQPSTLASGGGTADRCIKFWN 413
            ||||||||.:.||:.:|      ..|:.::.:|.|||:|:||.|.|...||||||||||||:|||
  Rat   328 LASGGNDNKLLVWNHSS------LSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWN 386

  Fly   414 VNNGTLMKSVDSKSQVCSLLFSRHYKELISAHGFANNQLTIWKYPTMVKQADLTGHTSRVLQMAM 478
            ...|..::.:|:.||||:|.:|:|..||:|.||::.||:.:||||::.:.|.||||:.|||.:||
  Rat   387 TLTGQPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAM 451

  Fly   479 SPDGSTVISAGADETLRLWNCFAPDPLASKKAVS 512
            ||||..:::...|||||.||.|: ...::|::||
  Rat   452 SPDGEAIVTGAGDETLRFWNVFS-KTRSTKESVS 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fzy	NP_477501.1	WD40	<218..498	CDD:441893	138/284 (49%)
		WD40 repeat	256..291	CDD:293791	12/34 (35%)
		WD40 repeat	297..332	CDD:293791	16/38 (42%)
		WD40 repeat	337..373	CDD:293791	20/35 (57%)
		WD40 repeat	386..424	CDD:293791	21/37 (57%)
		WD40 repeat	429..467	CDD:293791	17/37 (46%)
		WD40 repeat	473..513	CDD:293791	19/40 (48%)
Fzr1	NP_001101544.2	WD40	<200..472	CDD:441893	136/280 (49%)
		WD40 repeat	232..269	CDD:293791	12/36 (33%)
		WD40 repeat	275..311	CDD:293791	16/38 (42%)
		WD40 repeat	316..352	CDD:293791	21/41 (51%)
		WD40 repeat	359..397	CDD:293791	21/37 (57%)
		WD40 repeat	402..440	CDD:293791	17/37 (46%)
		WD40 repeat	446..487	CDD:293791	19/40 (48%)