Protein Alignment fzy and fzy-1

DIOPT Version :10

• Sequence 1: NP_477501.1
• Gene: fzy / 34968
• FlyBaseID: FBgn0001086
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_495051.1
• Gene: fzy-1 / 266859
• WormBaseID: WBGene00001511
• Length: 507
• Species: Caenorhabditis elegans
• Alignment Length: 494
• Identity: 144/494 - (29%)
• Similarity: 239/494 - (48%)
• Gaps: 63/494 - (12%)

  Fly    62 KTPGKSSEGKT------------KKSNTTPSKT----PGG---GDRFIPNRAATNFEL---AHFL 104
            :|||  |.|:|            :|.:.||::.    |..   ||||:..|...: ||   .|.:
 Worm     6 RTPG--SAGRTVRSSAQQNGLTMRKRDMTPTRNTNLLPNATFVGDRFLGVRLDQD-ELDHANHLM 67

  Fly   105 VNKDSGDKSDEENDKATSSNSNESNVQASAHKG-DRQKLISEVAQVGDSKGGRILCY-QNKAPAA 167
            .:|...:|.:..|..:..::..:.:|:..|.|. .|.|....:....|  |.||||| :|.||..
 Worm    68 TSKLYSNKENLNNSMSEPNSPEKKSVEGEALKQMMRHKSTGALTDADD--GDRILCYKKNLAPPP 130

  Fly   168 PETHNNPLKVVYSIKTPI----STKSGSRYIPTTSERILDAPDFINDYYLNLMDWSADNIVAVAL 228
            ...:.|..||:||..:.|    |.|..:|::..|:.::||.|....|.|...:||...|.|||||
 Worm   131 AIGYINQAKVLYSTNSVINPASSVKKSTRHVKETATKVLDGPGLTKDLYSRHLDWGCHNWVAVAL 195

  Fly   229 GSCVYLWNAQTGNIEQLTEFEEGDYAG---SLSWIQEGQILAIGNSTGAVELWDCSK------VK 284
            |..:||||.:|..|:.|.|.......|   |:.|.|||:.:::|.::|||:::|.::      |:
 Worm   196 GHELYLWNTETCVIKNLFEDNAPTNEGLITSVRWSQEGRYISLGYASGAVKIYDPNRPKTTEYVR 260

  Fly   285 RLRVMD-GHSARVGSLAW-NSFLVSSGSRDGTIVHHDVRAREHKLSTL---SGHTQEVCGLKWST 344
            .||.:. |.::|..|:|| ...:::.|.:.|.||:||||..:|.:|:.   :||.::|..|:||.
 Worm   261 ELRTLRVGGASRCASIAWRKQGVMTCGYKSGDIVNHDVRISQHVVSSWGGDNGHCRDVTALEWSA 325

  Fly   345 DFKYLASGGNDNLVNVWSAASGGVGTA---TDPLHKFNDHQAAVRALAWCPWQPSTLASGGGTAD 406
            |.....||.:|....:|........|.   .:|:...::|...||...:|.::...||:|||..|
 Worm   326 DENMCVSGSSDRTAKIWDGRHVRGSTVIQDPEPMFTIDEHTGQVRTAQFCSFRDGILATGGGIND 390

  Fly   407 RCIKFWNVNNGTLMK----SVDSKSQVCSLLFSRHYKELISA--HGFANNQLTIWKYPTMVKQA- 464
            ..:|.|:|.. ...|    :|.....|..::|:|.|.|:::|  .||    |.|:::....|.:
 Worm   391 GTVKLWDVKR-QFQKVRELNVCETGGVGGIVFNRPYSEMLTASDDGF----LRIYRFNANYKLSH 450

  Fly   465 DLTGHTSRVLQMAMSPDGSTVISAGADETLRLWNCFAPD 503
            ::......::.:..||....:| ...:|||:::..|..|
 Worm   451 EIQASNEPIMDLVGSPFDEVLI-GDMEETLKVFQLFNVD 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fzy	NP_477501.1	WD40	<218..498	CDD:441893	90/303 (30%)
		WD40 repeat	256..291	CDD:293791	13/41 (32%)
		WD40 repeat	297..332	CDD:293791	13/38 (34%)
		WD40 repeat	337..373	CDD:293791	10/38 (26%)
		WD40 repeat	386..424	CDD:293791	12/41 (29%)
		WD40 repeat	429..467	CDD:293791	11/40 (28%)
		WD40 repeat	473..513	CDD:293791	8/31 (26%)
fzy-1	NP_495051.1	WD40	221..484	CDD:475233	74/268 (28%)
		WD40 repeat	225..268	CDD:293791	13/42 (31%)
		WD40 repeat	273..312	CDD:293791	13/38 (34%)
		WD40 repeat	319..363	CDD:293791	10/43 (23%)
		WD40 repeat	369..409	CDD:293791	13/40 (33%)
		WD40 repeat	416..452	CDD:293791	11/39 (28%)
		WD40 repeat	459..482	CDD:293791	6/23 (26%)