Protein Alignment fzy and Cdc20b

DIOPT Version :10

• Sequence 1: NP_477501.1
• Gene: fzy / 34968
• FlyBaseID: FBgn0001086
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: XP_011242961.1
• Gene: Cdc20b / 238896
• MGIID: 3644472
• Length: 538
• Species: Mus musculus
• Alignment Length: 539
• Identity: 158/539 - (29%)
• Similarity: 231/539 - (42%)
• Gaps: 129/539 - (23%)

  Fly    29 KKLEASL--NGSVNTTRSVLSVSYNTSFSGVQAPTKTPGKSSEGKTKKSNTTPSKTP---GGGDR 88
            |:|.|.:  ..|..|||..||                |.:..|..:......||.||   ..|.:
Mouse    60 KRLSAEIPVASSPITTRWQLS----------------PARDPESSSSVEEGPPSHTPESLASGLK 108

  Fly    89 FIPNRAATNFEL-AHFLVNKDSGDKSDEENDKATSSNSNESNVQASAHKGDRQKLISEVAQVGDS 152
            ..|  ||....| :|   ||:|.....:.:.:..:|.........:..:|.::.|.        :
Mouse   109 ITP--AADTLTLRSH---NKNSPKTLSKGSSEVNNSTLRFCKTPLAGDRGWKENLA--------T 160

  Fly   153 KGGRILCYQNKAPAAPETHNNPLKVVYSIKTPISTKSGSRYIP------------TTSERILDAP 205
            ||.|.|                       ..|.||:.|::.|.            .|..|.....
Mouse   161 KGQRCL-----------------------NQPFSTQKGAQQIDGKMHLCEESRCVRTGCRFGARD 202

  Fly   206 DFI------------------------NDYYLNLMDWSADNIVAVALGSCVYLWNAQTGN-IEQL 245
            :|.                        ||||||.:|||:.|:||||||:.||:||.|..: ||.:
Mouse   203 EFYLRRFSGVYHSTCQPEVKIHLTGLRNDYYLNTLDWSSQNLVAVALGTSVYIWNGQNHSWIENI 267

  Fly   246 TEFEEGDYAGSLSWIQEGQILAIGNSTGAVELWDCSKVKRLRVMDGHSARVGSLAWNSFLVSSGS 310
            .......|..|::|::||..||:|.|.|.|:|||....|:||.:.||.:.||:|:||...:||||
Mouse   268 DLSVCCHYVSSVTWMREGSCLAVGTSEGEVQLWDAITKKQLRNLHGHLSVVGALSWNHCTLSSGS 332

  Fly   311 RDGTIVHHDVRAREHKLSTLSGHTQEVCGLKWSTDFKYLASGGNDNLVNVWSAASGGVGTATDPL 375
            |.|.:.|||||..:|::.||. |.:.||.||||.|.:.|:||.||.|:.:| ....|.|....||
Mouse   333 RLGRVHHHDVRVAQHRVGTLY-HKEAVCSLKWSPDGRLLSSGCNDGLLTIW-PHDPGAGVQGLPL 395

  Fly   376 HKFNDHQAAVR-----------------ALAWCPWQPSTLASGGGTADRCIKFWNVNNGTLMKSV 423
             |......||:                 |:.|||||...||.|||..|.|:...::|.|..:::.
Mouse   396 -KVIPQSTAVKLAFSRTPLPVLLLGTLQAMEWCPWQSEVLAVGGGVKDGCLHVLDINTGKNIQTP 459

  Fly   424 DSKSQVCSLLFSRHYKELISAHGFANNQLTIWKYPTMVKQADLTGHTSRVLQMAMSP----DGST 484
            .::||:|||::....||:.:..|...|.:.:|..||:.:..   |...:  |:...|    ...:
Mouse   460 STQSQICSLIWLPKTKEIATGQGAPKNDVALWTCPTLFRSG---GFFEK--QILTHPHLRTQSVS 519

  Fly   485 VISAGADET-----LRLWN 498
            :.:.|..||     |:.||
Mouse   520 LCTYGCPETHGILPLKCWN 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fzy	NP_477501.1	WD40	<218..498	CDD:441893	110/306 (36%)
		WD40 repeat	256..291	CDD:293791	16/34 (47%)
		WD40 repeat	297..332	CDD:293791	18/34 (53%)
		WD40 repeat	337..373	CDD:293791	16/35 (46%)
		WD40 repeat	386..424	CDD:293791	15/54 (28%)
		WD40 repeat	429..467	CDD:293791	10/37 (27%)
		WD40 repeat	473..513	CDD:293791	8/35 (23%)
Cdc20b	XP_011242961.1	WD40 repeat	236..273	CDD:293791	17/36 (47%)
		WD40	<244..>480	CDD:441893	95/238 (40%)
		WD40 repeat	277..313	CDD:293791	16/35 (46%)
		WD40 repeat	318..352	CDD:293791	17/33 (52%)
		WD40 repeat	359..394	CDD:293791	15/35 (43%)
		WD40 repeat	423..462	CDD:293791	15/38 (39%)