Protein Alignment fzy and fzr-1

DIOPT Version :9

• Sequence 1: NP_477501.1
• Gene: fzy / 34968
• FlyBaseID: FBgn0001086
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001379369.1
• Gene: fzr-1 / 174516
• WormBaseID: WBGene00001510
• Length: 704
• Species: Caenorhabditis elegans
• Alignment Length: 517
• Identity: 180/517 - (34%)
• Similarity: 262/517 - (50%)
• Gaps: 104/517 - (20%)

  Fly    20 TRGPAPRWKKKLEASLNGSVNTTRSVLS---VSYNTSFSGVQAPTK------------------- 62
            |||..|:.::.   :..|||:|...|::   :...|..||.::||.
 Worm   236 TRGIIPQLERN---AYGGSVDTVFPVVANEGIIDVTRISGAESPTMAQMMEPRLRCGADSVADIP 297

  Fly    63 -TPGKSSEGKTKKSNTTPSKTPGGGDRFIPNRAATNFELAHFLVNKDSGDKSDEENDKATSSNSN 126
             :|..|..|      .||:|.|.......|            :|.|.|..:|
 Worm   298 LSPAASING------DTPTKAPPPALPLSP------------IVQKQSPARS------------- 331

  Fly   127 ESNVQASAHKGDRQKLISEVAQVGDSK-GGRILCYQNKAPAAPETHNNPLKVVYSI------KTP 184
                           |.:..|:....| ||:          |..|..:|....:.:      :||
 Worm   332 ---------------LFTYSAKTTPVKYGGQ----------ATTTATSPFGGPFGVDSQRLLRTP 371

  Fly   185 ISTKSGSRYIPTTSERILDAPDFINDYYLNLMDWSADNIVAVALGSCVYLWNAQTGNIEQLTEF- 248
               :...|.:|....::||||:..:|:||||:|||:.|.::|.|.:|||||:|.|..:.:|.:.
 Worm   372 ---RKPIRKVPKNPYKVLDAPELQDDFYLNLVDWSSQNQLSVGLAACVYLWSATTSQVIKLCDLG 433

  Fly   249 --EEGDYAGSLSWIQEGQILAIGNSTGAVELWDCSKVKRLRVMDGHSARVGSLAWNSFLVSSGSR 311
              .|.|...|:.|..:|.:||:|.|.|..::||.:..|:.|.:.|||:|||.||||:..:.||||
 Worm   434 QTNEQDQVTSVQWCDKGDLLAVGTSRGVTQIWDVTTQKKTRELTGHSSRVGCLAWNADTICSGSR 498

  Fly   312 DGTIVHHDVRAREHKLS-TLSGHTQEVCGLKWSTDFKYLASGGNDNLVNVWSAASGGVGTATDPL 375
            |.||:|.|:|..::.:. .|:.|.|||||||||.|.:.||||||||.:.||:.      ...:|:
 Worm   499 DRTIMHRDIRCDDNDMGRKLTNHRQEVCGLKWSPDKQLLASGGNDNQLLVWNL------RRNEPI 557

  Fly   376 HKFNDHQAAVRALAWCPWQPSTLASGGGTADRCIKFWNVNNGTLMKSVDSKSQVCSLLFSRHYKE 440
            ..:..|.|||:||||.|.....|.|||||||||::|||......|:.||:.||||::.:|:|..|
 Worm   558 QTYTQHNAAVKALAWSPHHHGLLVSGGGTADRCLRFWNTLTAQPMQCVDTGSQVCNVAWSKHSSE 622

  Fly   441 LISAHGFANN--QLTIWKYPTMVKQADLTGHTSRVLQMAMSPDGSTVISAGADETLRLWNCF 500
            |:|.||::.|  |:.|||||::.....|.||..|||.:||||||.::::...|||||.|:.|
 Worm   623 LVSTHGYSFNHLQVIIWKYPSLQPVTKLVGHQYRVLYLAMSPDGESIVTGAGDETLRFWHVF 684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fzy	NP_477501.1	WD40	<208..500	CDD:225201	137/297 (46%)
		WD40	216..498	CDD:238121	131/287 (46%)
		WD40 repeat	256..291	CDD:293791	12/34 (35%)
		WD40 repeat	297..332	CDD:293791	16/35 (46%)
		WD40 repeat	337..373	CDD:293791	18/35 (51%)
		WD40 repeat	386..424	CDD:293791	19/37 (51%)
		WD40 repeat	429..467	CDD:293791	16/39 (41%)
		WD40 repeat	473..513	CDD:293791	15/28 (54%)
fzr-1	NP_001379369.1	WD40	400..681	CDD:238121	131/286 (46%)
		WD40 repeat	441..478	CDD:293791	12/36 (33%)
		WD40 repeat	484..520	CDD:293791	16/35 (46%)
		WD40 repeat	525..561	CDD:293791	19/41 (46%)
		WD40 repeat	568..606	CDD:293791	19/37 (51%)
		WD40 repeat	611..651	CDD:293791	16/39 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0305
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1220675at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820