Protein Alignment fzy and Cdc20

DIOPT Version :10

• Sequence 1: NP_477501.1
• Gene: fzy / 34968
• FlyBaseID: FBgn0001086
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_075712.2
• Gene: Cdc20 / 107995
• MGIID: 1859866
• Length: 499
• Species: Mus musculus
• Alignment Length: 534
• Identity: 271/534 - (50%)
• Similarity: 348/534 - (65%)
• Gaps: 43/534 - (8%)

  Fly     1 MSQFNFVSDLQNALIMDGE-TRGPAPRWKKKLEASLNGSVNTTRSVLSVSYNTSFSGVQAPTKTP 64
            |:||.|.|||.:.|.:|.. ...|..||::|.:.:...:.:..|:.     |.|.|..:.|.:||
Mouse     1 MAQFVFESDLHSLLQLDAPIPNAPVARWQRKAKEATGPAPSPMRAA-----NRSHSAGRTPGRTP 60

  Fly    65 GKSSEGKTKKSNTTPSKTPGGGDRFIPNRAATNFELAHFLVNK-----DSGDKSDEENDKATSSN 124
            ||||    .|..|||||.  |||||||.|:|:..|:|.||::|     |.|..:.:|:.||.|.|
Mouse    61 GKSS----SKVQTTPSKP--GGDRFIPQRSASQMEVASFLLSKENQPEDRGTPTKKEHQKAWSLN 119

  Fly   125 SNESNVQASAHKGDRQKLISEVAQVGDSKGGRILCYQNKAPAAPETHNNPLKVVYSIK-TPISTK 188
            .|..:|:.:                      :||....|...|||.:.|.|||:||.| ||.|::
Mouse   120 LNGFDVEEA----------------------KILRLSGKPQNAPEGYQNRLKVLYSQKATPGSSR 162

  Fly   189 SGSRYIPTTSERILDAPDFINDYYLNLMDWSADNIVAVALGSCVYLWNAQTGNIEQLTEFEE-GD 252
            ...||||:..:||||||:..|||||||:|||:.|::||||.:.||||||.:|:|.||.:.|: ||
Mouse   163 KTCRYIPSLPDRILDAPEIRNDYYLNLVDWSSGNVLAVALDNSVYLWNAGSGDILQLLQMEQPGD 227

  Fly   253 YAGSLSWIQEGQILAIGNSTGAVELWDCSKVKRLRVMDGHSARVGSLAWNSFLVSSGSRDGTIVH 317
            |..|::||:||..||:|.|...|:|||..:.||||.|..|||||.||:|||:::|||||.|.|.|
Mouse   228 YISSVAWIKEGNYLAVGTSNAEVQLWDVQQQKRLRNMTSHSARVSSLSWNSYILSSGSRSGHIHH 292

  Fly   318 HDVRAREHKLSTLSGHTQEVCGLKWSTDFKYLASGGNDNLVNVWSAASGGVGTATDPLHKFNDHQ 382
            ||||..||.::|||||:||||||:|:.|.::||||||||:||||.:..|..|.|  ||..|..||
Mouse   293 HDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNIVNVWPSGPGESGWA--PLQTFTQHQ 355

  Fly   383 AAVRALAWCPWQPSTLASGGGTADRCIKFWNVNNGTLMKSVDSKSQVCSLLFSRHYKELISAHGF 447
            .||:|:||||||.:.||:||||:||.|:.|||.:|..:.:||..|||||:|:|.|||||||.|||
Mouse   356 GAVKAVAWCPWQSNILATGGGTSDRHIRIWNVCSGACLSAVDVHSQVCSILWSPHYKELISGHGF 420

  Fly   448 ANNQLTIWKYPTMVKQADLTGHTSRVLQMAMSPDGSTVISAGADETLRLWNCFAPDPLASKKAVS 512
            |.|||.|||||||.|.|:|.|||:|||.:.|||||:||.||.||||||||.||..||...::...
Mouse   421 AQNQLVIWKYPTMAKVAELKGHTARVLGLTMSPDGATVASAAADETLRLWRCFEMDPALRREREK 485

  Fly   513 TSKGKQSVFRQSIR 526
            .|..|.|:..|.||
Mouse   486 ASVAKSSLIHQGIR 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fzy	NP_477501.1	WD40	<218..498	CDD:441893	173/280 (62%)
		WD40 repeat	256..291	CDD:293791	18/34 (53%)
		WD40 repeat	297..332	CDD:293791	21/34 (62%)
		WD40 repeat	337..373	CDD:293791	21/35 (60%)
		WD40 repeat	386..424	CDD:293791	20/37 (54%)
		WD40 repeat	429..467	CDD:293791	28/37 (76%)
		WD40 repeat	473..513	CDD:293791	23/39 (59%)
Cdc20	NP_075712.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	27..82		26/65 (40%)
		WD 1	182..221		25/38 (66%)
		WD40 repeat	188..224	CDD:293791	20/35 (57%)
		WD40	<190..471	CDD:441893	174/282 (62%)
		WD 2	224..263		19/38 (50%)
		WD40 repeat	229..266	CDD:293791	18/36 (50%)
		WD 3	266..303		24/36 (67%)
		WD40 repeat	272..307	CDD:293791	21/34 (62%)
		WD 4	307..346		24/38 (63%)
		WD40 repeat	312..352	CDD:293791	23/41 (56%)
		WD 5	353..395		24/41 (59%)
		WD40 repeat	359..397	CDD:293791	20/37 (54%)
		WD 6	397..438		30/40 (75%)
		WD40 repeat	402..440	CDD:293791	28/37 (76%)
		WD 7	441..480		27/38 (71%)