DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Syx5 and syx-5

DIOPT Version :9

Sequence 1:	NP_523582.4	Gene:	Syx5 / 34966	FlyBaseID:	FBgn0011708	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_505968.1	Gene:	syx-5 / 179611	WormBaseID:	WBGene00006373	Length:	413	Species:	Caenorhabditis elegans

Alignment Length:	318	Identity:	135/318 - (42%)
Similarity:	196/318 - (61%)	Gaps:	13/318 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   155 IFVMAARDRTGEFANAIRSLQARNITRAVNIRDPRKAKQVQSYSEFMMVARFIGKNIASTYAKLE 219
            |..|.:||||.||....:|.:.:  ..|..||...|.:.:....:|..:|:.|||.::.|.||:|
Worm   104 IITMPSRDRTSEFRATAKSYEMK--AAANGIRPQPKHEMLSESVQFNQLAKRIGKELSQTCAKME 166

  Fly   220 KLTMLAKKKSLFDDRPQEIQELTYIIKGDLNALNQQIARLQDISKDQRRHTNGKHLVS-HSSNMV 283
            ||...|||||.:::|.| |..|:.|:|.|:..||:||.:||:.||  ||..|.|:..| |...:|
Worm   167 KLAEYAKKKSCYEERSQ-IDHLSSIVKSDITGLNKQIGQLQEFSK--RRAGNMKNQNSGHIQLVV 228

  Fly   284 LALQSKLASMSTDFKQILEVRTENLKQQKTRRDQFSQGPGPLAAHTVSPSTAKQGSLLLSEENQ- 347
            :.||||||::..|::.:||:.||.:|.:|.|||:||.|.........|.|.|...|.||.::.|
Worm   229 VGLQSKLANVGKDYQSVLEISTETMKAEKNRRDKFSSGAAVPMGLPSSSSGANVRSKLLQDDEQH 293

  Fly   348 ---AVSIDMGSSDTTPLLSTQTQMAIYDDSDNYVQQRAETMQNIESTIVELGGIFQQLAHMVKEQ 409
               ::::|||:...   :.:|..|...|.|..|.|.|:.||..||.:|.|||.||.|||.:|.||
Worm   294 GSSSIALDMGALSN---MQSQQTMQQRDSSLEYAQARSNTMATIEGSISELGQIFSQLASLVSEQ 355

  Fly   410 EEIVERIDTNVADAELNIEAAHGEILKYFQSVSKNRWLMIKIFGVLIFFFLFFVVFMS 467
            .|::.|||:||.|..|||:.||.|:::|.|::||||||||::||||:.||:.||:|::
Worm   356 GEMITRIDSNVEDTALNIDMAHSELVRYLQNISKNRWLMIQVFGVLMVFFVVFVLFLT 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Syx5	NP_523582.4	SNARE_syntaxin5	379..451	CDD:277197	41/71 (58%)
syx-5	NP_505968.1	COG5325	123..382	CDD:227635	107/266 (40%)
syx-5	NP_505968.1	SNARE_syntaxin5	324..396	CDD:277197	40/71 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162098
Domainoid	1	1.000	145	1.000	Domainoid score	I2846
eggNOG	1	0.900	-	-		E1_KOG0812
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2381
Inparanoid	1	1.050	230	1.000	Inparanoid score	I2200
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53826
OrthoDB	1	1.010	-	-		D1297427at2759
OrthoFinder	1	1.000	-	-		FOG0003050
OrthoInspector	1	1.000	-	-		oto19765
orthoMCL	1	0.900	-	-		OOG6_102103
Panther	1	1.100	-	-	LDO	PTHR19957
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1315
SonicParanoid	1	1.000	-	-		X2031
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.800