DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17328 and ADR1

DIOPT Version :9

Sequence 1:	NP_609786.2	Gene:	CG17328 / 34962	FlyBaseID:	FBgn0028895	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_010502.3	Gene:	ADR1 / 851802	SGDID:	S000002624	Length:	1323	Species:	Saccharomyces cerevisiae

Alignment Length:	332	Identity:	74/332 - (22%)
Similarity:	116/332 - (34%)	Gaps:	79/332 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 GLPSVICNNCIYRLGVAFHFKQECENSDLRLRQYLGILESWRQDAATNTDFVEKPLLPQRDSDEE 112
            |.|.|..|:|         |.....|.              :|:....||  :.|:|....|...
Yeast    12 GFPVVDLNSC---------FSNGFNNE--------------KQEIEMETD--DSPILLMSSSASR 51

  Fly   113 EPVDAKVSKRRSRYQRKPP-------EEHKKRGPKPVPKMPHTCYECHKSFKCIAQLTQHIRTHT 170
            |.     |...|..||.|.       .....:..|.:.|:|.             .|..:.||.:
Yeast    52 EN-----SNTFSVIQRTPDGKIITTNNNMNSKINKQLDKLPE-------------NLRLNGRTPS 98

  Fly   171 GE-KPYQCSFCIQRFAQKYNLKVHERTHTGDKPFQCEICSKQFSALGNFQAH-QKIHLGVRDQVC 233
            |: :.:.|..|.:.||::.:||.|.|:||.:||:.|.:|::.|:.......| ||||.|...:..
Yeast    99 GKLRSFVCEVCTRAFARQEHLKRHYRSHTNEKPYPCGLCNRCFTRRDLLIRHAQKIHSGNLGETI 163

  Fly   234 SLCQKGFYTAGDLSKHMITHTG--------------IKNHHCDVCGKAFSRRRDMRTHKLKL--- 281
            |..:|...|.....|:..:...              :.....:...||.......|.:..||
Yeast   164 SHTKKVSRTITKARKNSASSVKFQTPTYGTPDNGNFLNRTTANTRRKASPEANVKRKYLKKLTRR 228

  Fly   282 --HPLESSTNHDIVDDDDDEAIDTDPVGLDT-----LDHAHFKCPDCDKAFDTADSLSLHFRTHA 339
              ...:|::::.:.|....|....|.|...|     ||   .|.|:.|.:||...:|.|:....:
Yeast   229 ASFSAQSASSYALPDQSSLEQHPKDRVKFSTPELVPLD---LKNPELDSSFDLNMNLDLNLNLDS 290

  Fly   340 ANNNLLN 346
            ..|..||
Yeast   291 NFNIALN 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17328	NP_609786.2	zf-AD	8..80	CDD:214871	7/31 (23%)
		COG5048	146..>211	CDD:227381	19/65 (29%)
		C2H2 Zn finger	149..169	CDD:275368	2/19 (11%)
		C2H2 Zn finger	177..197	CDD:275368	8/19 (42%)
		zf-H2C2_2	189..213	CDD:404364	10/23 (43%)
		C2H2 Zn finger	205..225	CDD:275368	6/20 (30%)
		C2H2 Zn finger	233..253	CDD:275368	4/19 (21%)
		zf-H2C2_2	245..270	CDD:404364	3/38 (8%)
		C2H2 Zn finger	261..282	CDD:275368	5/25 (20%)
		C2H2 Zn finger	318..338	CDD:275368	6/19 (32%)
ADR1	NP_010502.3	zf-C2H2	104..126	CDD:395048	8/21 (38%)
		C2H2 Zn finger	106..126	CDD:275368	8/19 (42%)
		zf-H2C2_2	118..143	CDD:404364	11/24 (46%)
		C2H2 Zn finger	134..155	CDD:275368	6/20 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24393
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100