DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17328 and Zfp524

DIOPT Version :9

Sequence 1:	NP_609786.2	Gene:	CG17328 / 34962	FlyBaseID:	FBgn0028895	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_079600.1	Gene:	Zfp524 / 66056	MGIID:	1916740	Length:	321	Species:	Mus musculus

Alignment Length:	221	Identity:	60/221 - (27%)
Similarity:	95/221 - (42%)	Gaps:	34/221 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 ATNTDFVEKPLLPQR-----DSDEEEPVDAKVSKRRSR------YQRKP---PEEHKKRGPK--P 141
            ||.::...|..||::     .|::|.|:.|.|....|.      .|..|   ||.....||:  .
Mouse    39 ATTSNRTLKSSLPRKRGRPPRSEQETPLTAPVDSGGSSDLLLIDDQGVPYTVPEGSAADGPQGSG 103

  Fly   142 VPKMPHTCYECHKSFKCIAQLTQHIRTHTGEKPYQCSFCIQRFAQKYNLKVHERTHTGDKPFQCE 206
            ..:.||.|..|.::|..::.|.:|..:|:..||:.|..|.:.|.:..:|:.|...|.|.:||:|.
Mouse   104 SKRAPHFCPVCLRAFPYLSDLERHSISHSELKPHVCKDCGKTFKRSSHLRRHCNIHAGLRPFRCV 168

  Fly   207 ICSKQFSALGNFQAHQKIHLGVRDQVCSLCQKGFYTAGDLSKHMITHTGIKNHHCDVCGKAFSRR 271
            :|.::|...|....|.:||.|.|...|..|:..|..|..|.:|      .|..|.::.|.
Mouse   169 LCPRRFREAGELAHHHRIHSGERPYQCPSCRVRFTEANTLRRH------YKRKHPELVGM----- 222

  Fly   272 RDMRTHKLKLHPLESSTNHDIVDDDD 297
                  .::|.|....| ..:.|||:
Mouse   223 ------PVRLCPPNPRT-QPLWDDDE 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17328	NP_609786.2	zf-AD	8..80	CDD:214871
		COG5048	146..>211	CDD:227381	21/64 (33%)
		C2H2 Zn finger	149..169	CDD:275368	5/19 (26%)
		C2H2 Zn finger	177..197	CDD:275368	5/19 (26%)
		zf-H2C2_2	189..213	CDD:404364	8/23 (35%)
		C2H2 Zn finger	205..225	CDD:275368	5/19 (26%)
		C2H2 Zn finger	233..253	CDD:275368	6/19 (32%)
		zf-H2C2_2	245..270	CDD:404364	5/24 (21%)
		C2H2 Zn finger	261..282	CDD:275368	1/20 (5%)
		C2H2 Zn finger	318..338	CDD:275368
Zfp524	NP_079600.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..80		11/40 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	86..105		5/18 (28%)
		COG5048	<102..218	CDD:227381	36/121 (30%)
		C2H2 Zn finger	111..131	CDD:275368	5/19 (26%)
		C2H2 Zn finger	139..159	CDD:275368	5/19 (26%)
		C2H2 Zn finger	167..187	CDD:275368	5/19 (26%)
		C2H2 Zn finger	195..216	CDD:275368	7/26 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	248..321
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000