DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17328 and Zfp566

DIOPT Version :9

Sequence 1:	NP_609786.2	Gene:	CG17328 / 34962	FlyBaseID:	FBgn0028895	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_001128198.1	Gene:	Zfp566 / 502316	RGDID:	1563239	Length:	386	Species:	Rattus norvegicus

Alignment Length:	228	Identity:	76/228 - (33%)
Similarity:	104/228 - (45%)	Gaps:	33/228 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 EEPVDAKVSKRRSRYQRKPPEEHKKRGPKPVPKMPHTCYECHKSFKCIAQLTQHIRTHTGEKPYQ 176
            |:|.:.|...:..|:.......||..    ..|.|..|.||.|:|.|.:.||:|.|.|||||||:
  Rat   164 EKPYECKDCGKTFRHPSGLTHHHKIH----TGKKPFECKECGKTFICGSDLTRHHRIHTGEKPYE 224

  Fly   177 CSFCIQRFAQKYNLKVHERTHTGDKPFQCEICSKQFSALGNFQAHQKIHLGVRDQVCSLCQKGFY 241
            |..|.:.|:...|...|:|.|||:||::|:.|.|.||:..||..||:||.|.:...|..|...|.
  Rat   225 CKDCGKAFSSGSNFTRHQRIHTGEKPYECKECGKAFSSGSNFTQHQRIHTGEKPYECKECGNAFS 289

  Fly   242 TAGDLSKHMITHTGIKNHHCDVCGKAFSRRRDMRTHKLKLHPLESSTNHDIVDDDDDEAIDTDPV 306
            .:..|.||...|||.|.:.|..|.|||....|:..|: ::|..|..
  Rat   290 QSSQLIKHQRIHTGEKPYECKECEKAFRSGSDLTRHQ-RIHTGEKP------------------- 334

  Fly   307 GLDTLDHAHFKCPDCDKAFDTADSLSLHFRTHA 339
                     ::|..|.||:..:..|..|.|.||
  Rat   335 ---------YECKICGKAYSQSSQLISHHRIHA 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17328	NP_609786.2	zf-AD	8..80	CDD:214871
		COG5048	146..>211	CDD:227381	31/64 (48%)
		C2H2 Zn finger	149..169	CDD:275368	10/19 (53%)
		C2H2 Zn finger	177..197	CDD:275368	6/19 (32%)
		zf-H2C2_2	189..213	CDD:404364	11/23 (48%)
		C2H2 Zn finger	205..225	CDD:275368	9/19 (47%)
		C2H2 Zn finger	233..253	CDD:275368	6/19 (32%)
		zf-H2C2_2	245..270	CDD:404364	12/24 (50%)
		C2H2 Zn finger	261..282	CDD:275368	7/20 (35%)
		C2H2 Zn finger	318..338	CDD:275368	7/19 (37%)
Zfp566	NP_001128198.1	KRAB	5..45	CDD:396083
		zf-C2H2	167..189	CDD:395048	4/21 (19%)
		C2H2 Zn finger	169..189	CDD:275368	4/19 (21%)
		COG5048	<193..355	CDD:227381	66/190 (35%)
		C2H2 Zn finger	197..217	CDD:275368	10/19 (53%)
		C2H2 Zn finger	225..245	CDD:275368	6/19 (32%)
		C2H2 Zn finger	253..273	CDD:275368	9/19 (47%)
		C2H2 Zn finger	281..301	CDD:275368	6/19 (32%)
		C2H2 Zn finger	309..329	CDD:275368	7/20 (35%)
		C2H2 Zn finger	337..357	CDD:275368	7/19 (37%)
		C2H2 Zn finger	365..384	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000