DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment heix and ubiad1

DIOPT Version :9

Sequence 1:	NP_523581.1	Gene:	heix / 34961	FlyBaseID:	FBgn0028375	Length:	359	Species:	Drosophila melanogaster
Sequence 2:	NP_001186655.1	Gene:	ubiad1 / 558410	ZFINID:	ZDB-GENE-030131-3205	Length:	336	Species:	Danio rerio

Alignment Length:	295	Identity:	172/295 - (58%)
Similarity:	213/295 - (72%)	Gaps:	5/295 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 KLKTYLLALRPWSLSASLVPTLLGSALAYRSQWAEEFSLATFFLTAFTVVTVHCAGNVVNTYFDF 124
            |...|:|||||||.||||.|..|||||||:.:.:.:  |....:.|..|:.||.|||:||||:||
Zfish    43 KCAAYVLALRPWSFSASLTPVALGSALAYKLEGSVD--LLLLLVCAVAVLLVHGAGNLVNTYYDF 105

  Fly   125 IKGIDKQKADDRTLVDHILTKDEVVSLGAILYMAGCGGFVLLAVLSPAKMEHLALIYFGGLSSSF 189
            .||||.:|:|||||||.||...:||..||:||.|||....||..||..|:|||||||||||||||
Zfish   106 SKGIDHKKSDDRTLVDQILKPQDVVMFGAVLYSAGCLCATLLYFLSSLKLEHLALIYFGGLSSSF 170

  Fly   190 LYTGGIGFKYIALGDLVILILFGPISVLFAFMSQTGHLDWTTMGYAIPLALNTEAILHSNNTRDA 254
            |||||||.||:||||:||||.|||::|:||...|.|:|....:.||:|||||||||||||||||.
Zfish   171 LYTGGIGLKYVALGDVVILITFGPLAVMFAHAVQVGYLSVLPLVYAVPLALNTEAILHSNNTRDM 235

  Fly   255 DNDRRAGIVTLAILIGRTASHVLYAMLLFAPYSLFFIFGLKYSLWFLLPLVTLPQAFQIEKRFRN 319
            |:|::|||||||||:|.|.|:|:|.:|||.||.||.|...:|::...|||:|||.||.:|::||.
Zfish   236 DSDKQAGIVTLAILLGPTLSYVIYNLLLFVPYLLFCILATRYTISMALPLLTLPMAFPLERQFRC 300

  Fly   320 EQTMHLVPRQTAKLNFFFGILYVVACCCAHQ--LP 352
             :....:|::|||||...|:.||.....|.|  ||
Zfish   301 -RCYAKIPQKTAKLNLLMGLFYVFGIILAPQGSLP 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
heix	NP_523581.1	PT_UbiA_UBIAD1	65..344	CDD:260125	166/278 (60%)
ubiad1	NP_001186655.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..22
ubiad1	NP_001186655.1	PT_UbiA_UBIAD1	48..324	CDD:260125	166/278 (60%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593706
Domainoid	1	1.000	284	1.000	Domainoid score	I1603
eggNOG	1	0.900	-	-		E1_COG1575
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8336
Inparanoid	1	1.050	324	1.000	Inparanoid score	I2468
OMA	1	1.010	-	-		QHG61276
OrthoDB	1	1.010	-	-		D1146311at2759
OrthoFinder	1	1.000	-	-		FOG0006610
OrthoInspector	1	1.000	-	-		oto39548
orthoMCL	1	0.900	-	-		OOG6_103718
Panther	1	1.100	-	-	LDO	PTHR13929
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4813
SonicParanoid	1	1.000	-	-		X4847
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800