DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17329 and CG13025

DIOPT Version :9

Sequence 1:	NP_609784.2	Gene:	CG17329 / 34958	FlyBaseID:	FBgn0028896	Length:	162	Species:	Drosophila melanogaster
Sequence 2:	NP_001261971.1	Gene:	CG13025 / 39874	FlyBaseID:	FBgn0036660	Length:	608	Species:	Drosophila melanogaster

Alignment Length:	182	Identity:	56/182 - (30%)
Similarity:	80/182 - (43%)	Gaps:	46/182 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEKIEKELERTEQQQQ--EPTEPSNGNLEEQVRKLRDHNLRVKHLNTQRRRILRLLQGKMLQYAT 63
            :|.::..:|..||:.|  |..||....:...:  |.|    ..||.:..|. .|..||:..:..:
  Fly    33 VEGLQPAVEIDEQRDQPGENAEPEQPRVPPLI--LVD----PPHLPSPPRN-SRRNQGEEQEVIS 90

  Fly    64 LE--------ERLHRIGELVLIAELHSGVKTLNQR-------LDRMVENSTCSICLLPWTDNGIH 113
            ||        :||....:           |:|.:.       :|...:..||.|||..|..:|.|
  Fly    91 LETPSPPKKRKRLSAAAD-----------KSLKKSPEGKPIVVDDEDDGMTCPICLDSWEMSGEH 144

  Fly   114 RLVSLRCGHLFGSSCIHMAIRRNHR------CPICRRRA-----RHFHVRRI 154
            ||||||||||||.|||...:..:||      ||.|:.:|     ||.:.:||
  Fly   145 RLVSLRCGHLFGESCIRRWLNESHRQSSVKVCPQCKTKATFRDIRHLYAKRI 196

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17329	NP_609784.2	zf-RING_2	99..143	CDD:290367	27/49 (55%)
CG13025	NP_001261971.1	zf-RING_2	130..180	CDD:290367	27/49 (55%)
		WD40	<293..445	CDD:295369
		WD40	<318..>415	CDD:225201
		WD40 repeat	339..375	CDD:293791
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447443
Domainoid	1	1.000	54	1.000	Domainoid score	I4143
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7722
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1451258at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5303
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.830