DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pkaap and RAX1

DIOPT Version :9

Sequence 1:	NP_609783.1	Gene:	pkaap / 34957	FlyBaseID:	FBgn0040079	Length:	622	Species:	Drosophila melanogaster
Sequence 2:	NP_014945.3	Gene:	RAX1 / 854477	SGDID:	S000005827	Length:	435	Species:	Saccharomyces cerevisiae

Alignment Length:	233	Identity:	47/233 - (20%)
Similarity:	85/233 - (36%)	Gaps:	54/233 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 DIFTYNSRLSMNLASIVNDPNCLSYFVQYLDTRQALPLIKFYLDIE-----NFKRA--------- 151
            |::|:.:.||       ..|..::|...::|......|.|.|:::.     ||.:.
Yeast    38 DLWTFYTFLS-------QFPYAINYLDFWVDLMTHTRLCKNYIELVRKSLINFPQEQQQNGSTST 95

  Fly   152 -------ALTQEKEEPEEPPRKAIEQSSPHKDDKDVPELKTLCDL---------SMRKPLTDDEK 200
                   ||.:|.....|.|.|.:|.|.|     |||....|.:|         ..::.|.:::.
Yeast    96 ATFDLLNALIEEGHLDPEAPDKLLENSGP-----DVPFSPKLNELLGDWKHQSGIGQEALRNEDV 155

  Fly   201 SRIYAETNKQLNRQKSGTDSVLNAELSRASISDAIAIYQKYLIVNASLQVELPIVILAHISLLLC 265
            :.|..|..|: ..|:.|...:...:|    :..|:.:...||:     ..|.....|::|.:...
Yeast   156 ALIVDEIMKR-RSQQDGKPQITTKQL----LHSAVGLCNTYLV-----SPEQSERYLSNIPMETR 210

  Fly   266 GR--DKSECSKPIPASCFDEAREFVLEQLERDHVQGFL 301
            .|  :..:..:......||:.:....:.||.|....||
Yeast   211 NRIIESVQIERKYDIEIFDDLKNLTYQFLEMDCFPKFL 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pkaap	NP_609783.1	RGS	109..308	CDD:295367	45/225 (20%)
		RGS_AKAP2_2	324..444	CDD:188676
		AKAP10_AKB	561..605	CDD:214003
RAX1	NP_014945.3	RGS	<189..255	CDD:214613	13/65 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343494
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR13155
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030