Protein Alignment pkaap and Akap10

DIOPT Version :10

• Sequence 1: NP_609783.1
• Gene: pkaap / 34957
• FlyBaseID: FBgn0040079
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_001108078.1
• Gene: Akap10 / 360540
• RGDID: 1308869
• Length: 662
• Species: Rattus norvegicus
• Alignment Length: 577
• Identity: 155/577 - (26%)
• Similarity: 256/577 - (44%)
• Gaps: 124/577 - (21%)

  Fly   107 SRLSMNLASIVNDPNCLSYFVQYLDTRQALPLIKFYLDIENF--------KRAALTQEKE----E 159
            |.||..|..::.|...|.||:|:::.|:...|:||:|:.|:|        :..:|...|:    |
  Rat   120 SSLSKTLEQVLRDSVVLPYFLQFMELRRMEHLVKFWLEAESFHSTTWSRIRAHSLNTVKQSSLAE 184

  Fly   160 PEEPPRKA------IEQSSPHK--DDKDVPELKTL---CDLSMRKPLTDDEKSRIY----AETNK 209
            |..|.:|.      :.:|...:  |....|.|.|.   .|||.|   |.:.::.:.    ..:..
  Rat   185 PVSPSKKQETTASFVTESLDRRLGDSSSAPLLLTQSEGTDLSSR---TQNTQNHLLLSQECHSTH 246

  Fly   210 QLNRQ--KSGTDSV-------------------------LNAELSRASISDAIAIYQKYLIVNAS 247
            .|:.:  ::||..:                         |:.:|.::...||:..:.||:..:|:
  Rat   247 SLHHEVARTGTHQISTDSQESSSRLAVASRNSCSSPLRELSEKLMKSIEQDAVNTFTKYISPDAA 311

  Fly   248 LQVELPIVILAHISLLLCGRDKSECSKPIPASCFDEAREFVLEQLERDHVQGFLQSGYYSTYCLE 312
            ..:.:...:...|...:||.|..     :..:||..|:..|...:|::|...||:|.::..|.:|
  Rat   312 KPIPITEAMRNDIIAKICGEDGQ-----VDPNCFVLAQAVVFSAMEQEHFSEFLRSHHFCKYQIE 371

  Fly   313 LIEGGSVNIYDVLNSELALFYFTEYLEQRQERECLEFWITAINFRKSFACGEEKEEDRKAAQSDA 377
            ::..|:|.:.|:|..|.|||||:||:|:......|:||:.|.||:...| .::.:.|.:.||:||
  Rat   372 VLTSGTVYLADILFCESALFYFSEYMEKEDAVNILQFWLAADNFQSQLA-AKKGQYDGQEAQNDA 435

  Fly   378 MIIYDKYFSLQSECRLWMSQKLRLRVEQAIC-----APNEQWQAFDLALLVTAKYLEQKYFADFL 437
            ||:||||||||:...|.....:||.:|..||     .||    .|...|......:|:.:...||
  Rat   436 MILYDKYFSLQATHPLGFDDVVRLEIESNICREGGPLPN----CFTTPLRQAWTTMEKVFLPGFL 496

  Fly   438 KSHIFDNYVNEL--KVKRD------------NSTTHPNLQHTLSLRRAGKSSNGQQQRHRKTLSM 488
            .|:::..|:|:|  .|:.|            .|...|...|      :|.|.....|...|..|:
  Rat   497 SSNLYYKYLNDLIHSVRGDEFLGGNVSLAAHGSVCLPEESH------SGGSDGSTAQSSVKKASI 555

  Fly   489 SDCTHISQHNTLLASMDQAPSKTALNHQSGNLNIDARQLTNPQLLWQRP-VGALKFGFVNSLGRY 552
            .          :|.:.|:|            :.:||..| :|:.|:||. .|.:.||.|:.||::
  Rat   556 K----------ILKNFDEA------------IVVDAASL-DPESLYQRTYAGKMSFGRVSDLGQF 597

  Fly   553 ERDFEAVDAVALKSQPWSLSVSGSKLKNAMRKLVNLPEDNVQEEIAWQVAEMIVRDV 609
            .|:.|        .:|......|.....||:|.|....|..|||:||::|:|||.||
  Rat   598 IRESE--------PEPDVKKSKGFMFSQAMKKWVQGNTDEAQEELAWKIAKMIVSDV 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pkaap	NP_609783.1	RGS	109..308	CDD:470619	54/252 (21%)
		RGS_AKAP2_2	324..444	CDD:188676	46/124 (37%)
		AKAP10_AKB	561..605	CDD:214003	13/43 (30%)
Akap10	NP_001108078.1	RGS_AKAP2_1	122..367	CDD:188689	54/252 (21%)
		RGS_AKAP2_2	383..503	CDD:188676	46/124 (37%)
		AKAP10_AKB	618..662	CDD:214003	16/29 (55%)